Evidence map›Paper›PMID 37440055›Full record

ArticleAdvances in experimental medicine and biology2023

Compensatory Cone-Mediated Mechanisms in Inherited Retinal Degeneration Mouse Models: A Functional and Gene Expression Analysis.

Alicia A Brunet, David M Hunt, Carla Mellough, Alan R Harvey, Livia S Carvalho

Abstract read
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In one paragraph

Article in Advances in experimental medicine and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Alicia A BrunetCentre for Ophthalmology and Visual Sciences, The University of Western Australia, Crawley, WA, Australia. alicia.brunet@research.uwa.edu.au.
David M HuntCentre for Ophthalmology and Visual Sciences, The University of Western Australia, Crawley, WA, Australia.
Carla MelloughCentre for Ophthalmology and Visual Sciences, The University of Western Australia, Crawley, WA, Australia.
Alan R HarveySchool of Human Sciences, The University of Western Australia, Crawley, WA, Australia.
Livia S CarvalhoCentre for Ophthalmology and Visual Sciences, The University of Western Australia, Crawley, WA, Australia.
Lions Eye Institute · AUUniversity of Western Australia · AUPerron Institute for Neurological and Translational Science · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The retina undergoes compensatory changes in response to progressive photoreceptor loss/dysfunction; however, studies of inherited retinal diseases (IRDs) often lack a temporal connection between gene expression and visual function. Here, we used three mouse models of IRD - Cnga3

Indexed as

Retinal DegenerationAnimalsDisease Models, AnimalElectroretinographyGene Expression ProfilingMiceRetinaRetinal Cone Photoreceptor CellsAchromatopsiaCell deathcnga3cpfl1Inherited retinal diseaseMechanismsrd1Retinitis pigmentosaVision

Identifiers

PMID37440055
OpenAlexW4384126719

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.