Evidence map›Paper›PMID 37440053›Full record

ArticleAdvances in experimental medicine and biology2023

A Novel Mouse Model for Late-Onset Retinal Degeneration (L-ORD) Develops RPE Abnormalities Due to the Loss of C1qtnf5/Ctrp5.

Shyamanga Borooah, Anil Chekuri, Shikha Pachauri, Bhubananda Sahu, Marina Vorochikhina, John J Suk, Dirk-Uwe Bartsch, Venkata R M Chavali, Monica M Jablonski, Radha Ayyagari

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In one paragraph

Article in Advances in experimental medicine and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Shyamanga BorooahShiley Eye Institute, University of California San Diego, La Jolla, CA, USA.
Anil ChekuriShiley Eye Institute, University of California San Diego, La Jolla, CA, USA.
Shikha PachauriShiley Eye Institute, University of California San Diego, La Jolla, CA, USA.
Bhubananda SahuShiley Eye Institute, University of California San Diego, La Jolla, CA, USA.
Marina VorochikhinaShiley Eye Institute, University of California San Diego, La Jolla, CA, USA.
John J SukShiley Eye Institute, University of California San Diego, La Jolla, CA, USA.
Dirk-Uwe BartschShiley Eye Institute, University of California San Diego, La Jolla, CA, USA.
Venkata R M ChavaliShiley Eye Institute, University of California San Diego, La Jolla, CA, USA.
Monica M JablonskiDepartment of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN, USA.
Radha AyyagariShiley Eye Institute, University of California San Diego, La Jolla, CA, USA. rayyagari@health.ucsd.edu.
University of California San Diego · USPenn Presbyterian Medical Center · USUniversity of Tennessee Health Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Late-onset retinal degeneration (L-ORD) is an autosomal dominant macular dystrophy resulting from mutations in the gene CTRP5/C1QTNF5. A mouse model (Ctrp5

Indexed as

Macular DegenerationRetinal DegenerationAnimalsHumansMiceMutationRetinaRetinal Pigment EpitheliumBLamDCTRP5/C1QTNF5Fundus autofluorescent spotsGene knock-out mouse modelLate-onset retinal degeneration (L-ORD)Retinal and RPE pathologySub-RPE deposits

Identifiers

PMID37440053
OpenAlexW4384126873

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.