ArticleMicrobiology spectrum2023
Multi-Omics Reveals the Impact of Exogenous Short-Chain Fatty Acid Infusion on Rumen Homeostasis: Insights into Crosstalk between the Microbiome and the Epithelium in a Goat Model.
Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 28 citations in OpenAlex.
- Dietary theabrownins alleviate age-related declines in productive performance and egg quality by improving intestinal health in laying hens.Journal of animal science and biotechnology · 2026Article
- Host-microbial co-regulation mediates rumen volatile fatty acid production and utilization in dairy cows.Science China. Life sciences · 2026Article
- Rumen-Plasma-Milk Metabolomics Profiling Revealed Metabolic Alterations Associated with Milk Fat Synthesis in Chinese Holstein Cows.Animals : an open access journal from MDPI · 2026Article
- In Vitro Evaluation of Spearmint Essential Oil (Animals : an open access journal from MDPI · 2026Article
- Multi-Omics Analysis Reveals That Alkaline Mineral Complex Reshapes Rumen Mucosal Microbiota and Metabolites and Enhances Rumen Epithelial Barrier Function in Fattening Cattle.Animals : an open access journal from MDPI · 2026Article
- Feeding different proportion of oat silage in feedlot diets: effects on rumen function and meat quality of Tibetan sheep.AMB Express · 2026Article
- Lyophilized rumen fluid from goats fed different roughage-based diets: fermentation characteristics, microbial communities, and post-reconstitutionFrontiers in microbiology · 2026Article
- Multi-omics analysis reveals the mechanism of rosemary extract supplementation in increasing milk production in Sanhe dairy cows via the "rumen-serum-milk" metabolic pathway.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Mucus-penetrating microbiota drive chronic low-grade intestinal inflammation and metabolic dysregulation.Gut microbes · 2025Article
- Article
- Melatonin Promotes Muscle Growth and Redirects Fat Deposition in Cashmere Goats via Gut Microbiota Modulation and Enhanced Antioxidant Capacity.Antioxidants (Basel, Switzerland) · 2025Article
- Cooling redistributed endotoxin across different biofluids via modulating the ruminal microbiota and metabolome without altering quorum sensing signal levels in heat-stressed beef bulls.Animal microbiome · 2025Article
- Role of the Rumen Epithelium and Associated Changes Under High-Concentrate Diets.International journal of molecular sciences · 2025Review
- Identification of transcriptional regulators and signaling pathways mediating postnatal rumen growth and functional maturation in cattle.Journal of animal science · 2025Article
- Recent nutritional strategies and feed additives to stimulate proper rumen development in young goats.Translational animal science · 2025Article
- Microbial insights into ruminal fiber degradation and feed efficiency of Hu sheep.Frontiers in microbiology · 2025Article
- Reciprocal regulation of rumen microbiota and epithelial genes in response to small peptide supplementation for feed efficiency in beef cattle.Frontiers in veterinary science · 2025Article
- Article
- Rumen Development of Tianhua Mutton Sheep Was Better than That of Gansu Alpine Fine Wool Sheep under Grazing Conditions.Animals : an open access journal from MDPI · 2024Article
- Ruminal microbiota-host crosstalks promote ruminal epithelial development in neonatal lambs with alfalfa hay introduction.mSystems · 2024Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emerging data have underscored the significance of exogenous supplementation of butyrate in the regulation of rumen development and homeostasis. However, the effects of other short-chain fatty acids (SCFAs), such as acetate or propionate, has received comparatively less attention, and the consequences of extensive exogenous SCFA infusion remain largely unknown. In our study, we conducted a comprehensive investigation by infusion of three SCFAs to examine their respective roles in regulating the rumen microbiome, metabolism, and epithelium homeostasis. Data demonstrated that the infusion of sodium acetate (SA) increased rumen index while also promoting SCFA production and absorption through the upregulation of SCFA synthetic enzymes and the mRNA expression of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.