Evidence map›Paper›PMID 37439462›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Zinc-Organometallic Framework Vaccine Controlled-Release Zn

Lin Ding, Minli Liang, Yuanyuan Li, Mei Zeng, Meiting Liu, Wei Ma, Fuming Chen, Chenchen Li, Rui L Reis, Fu-Rong Li and 1 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 59 citations in OpenAlex.

  1. Review
  2. Circulating CD28Journal of translational medicine · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Metallic nanomedicine in cancer immunotherapy.Acta pharmaceutica Sinica. B · 2025
    Review
  10. Review
  11. Article
  12. Review
  13. CeOAsian journal of pharmaceutical sciences · 2025
    Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Lin DingThe First Affiliated Hospital (Shenzhen People's Hospital), Southern University of Science and Technology, Shenzhen, 518055, China.
Minli LiangThe First Affiliated Hospital (Shenzhen People's Hospital), Southern University of Science and Technology, Shenzhen, 518055, China.
Yuanyuan LiClinical Laboratory, Jiaozuo Women's and Child's Hospital, Jiaozuo, 454001, China.
Mei ZengSchool of Pharmacy, Guangdong Medical University, Dongguan, 523109, China.
Meiting LiuSchool of Pharmacy, Guangdong Medical University, Dongguan, 523109, China.
Wei MaTranslational Medicine Collaborative Innovation Center, The First Affiliated Hospital (Shenzhen People's Hospital), Southern University of Science and Technology, Shenzhen, 518020, China.
Fuming ChenTranslational Medicine Collaborative Innovation Center, The First Affiliated Hospital (Shenzhen People's Hospital), Southern University of Science and Technology, Shenzhen, 518020, China.
Chenchen LiKey Laboratory of Tropical Translational Medicine of Ministry of Education, School of Pharmacy and The First Affiliated Hospital, Hainan Medical University, Haikou, 570228, China.
Rui L Reis3B's Research Group, I3Bs-Research Institute on Biomaterials Biodegradables and Biomimetics, University of Minho, Guimarães, 4805-017, Portugal.
Fu-Rong LiThe First Affiliated Hospital (Shenzhen People's Hospital), Southern University of Science and Technology, Shenzhen, 518055, China.
Yanli WangKey Laboratory of Tropical Translational Medicine of Ministry of Education, School of Pharmacy and The First Affiliated Hospital, Hainan Medical University, Haikou, 570228, China.ORCID 0000-0003-1571-9918
Southern University of Science and Technology · CNGuangdong Medical College · CNHainan Medical University · CNJiaozuo University · CNUniversity of Minho · PT

Funding

Guangdong Basic and Applied Basic Research Foundation 2021A1515110657Guangdong Basic and Applied Basic Research Foundation 2022A1515010056National Key Research and Development Program of China No. 2022YFC2305000National Natural Science Foundation of China No. 82001755Shenzhen Science and Technology Program RCBS20210609104513023
6 · The paper itself

Abstract

Tumor extracellular matrix (ECM) not only forms a physical barrier for T cells infiltration, but also regulates multiple immunosuppressive pathways, which is an important reason for immunotherapy failure. The cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes (cGAS-STING) pathway plays a key role in activating CD8

Indexed as

Cancer VaccinesNeoplasmsCD8-Positive T-LymphocytesDelayed-Action PreparationsDendritic CellsHumansImmunotherapyMatrix Metalloproteinase 2NucleotidyltransferasesTumor MicroenvironmentZincCancer VaccinesDelayed-Action PreparationsMatrix Metalloproteinase 2NucleotidyltransferasesZincimmunotherapytumor extracellular matrixvaccinezinc-organometallic frameworkZn2+

Identifiers

PMID37439462
PMCPMC10520680
OpenAlexW4384119683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.