ArticleHaematologica2024
Actin-bundling protein L-plastin promotes megakaryocyte rigidity and dampens proplatelet formation.
Abstract readLetter
In one paragraph
Article in Haematologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- A Nanobody-LNP Platform for Targeting and Relicensing Dendritic Cells for Potent Cancer Immunotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- What It Takes To Be a Platelet: Evolving Concepts in Platelet Production.Circulation research · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Li GuoProgram in Molecular Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT; Division of Hematology and Hematologic Malignancies, Department of Internal Medicine, University of Utah, Salt Lake City, UT; Bloodworks Research Institute, Seattle, WA; Hematology Division, University of Washington, Seattle, WA.
Shancy JacobProgram in Molecular Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT.
Bhanu Kanth ManneProgram in Molecular Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT.
E Motunrayo KolawoleDepartment of Pathology, University of Utah, Salt Lake City, UT.
Siqi GuoProgram in Molecular Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT; Applied Mathematics, Department of Mathematics, University of Utah, Salt Lake City, UT.
Xiang WangHSC Cell Imaging Core, School of Medicine, University of Utah, Salt Lake City, UT.
Darian MurrayProgram in Molecular Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT.
Emilia A TugolukovaProgram in Molecular Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT.
Irina PortierProgram in Molecular Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT.
Yasuhiro KosakaProgram in Molecular Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT.
Cindy BarbaDepartment of Pathology, University of Utah, Salt Lake City, UT.
Matthew T RondinaProgram in Molecular Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT; Department of Pathology, University of Utah, Salt Lake City, UT; Department of Internal medicine, University of Utah, Salt Lake City, UT; George E. Wahlen Department of Veterans Affairs Medical Center, Department of Internal Medicine, and Geriatric Research, Education, and Clinical Center (GRECC), Salt Lake City, UT.
Brian EvavoldDepartment of Pathology, University of Utah, Salt Lake City, UT.
Celeste MorleyPediatrics, Infectious Diseases, Washington University, St. Louis, MO; Pathology and Immunology, Washington University, St. Louis, MO.
Seema BhatlekarProgram in Molecular Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT. saseems@gmail.com.
Paul F BrayProgram in Molecular Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT; Division of Hematology and Hematologic Malignancies, Department of Internal Medicine, University of Utah, Salt Lake City, UT. Paul.bray@hsc.utah.edu.
Funding
UTAH REGIONAL CANCER CENTERP30CA042014 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Jared P Rutter · 1986 to 2026
$72.6MNew Therapies to Restore Vascular Integrity During SepsisR01HL130541 · NHLBI · UNIVERSITY OF UTAH · PI ODELBERG, SHANNON J, WEYRICH, ANDREW S · 2016 to 2020
$3.7MDefining how TCR strength of signal modulates Treg functionR01AI169835 · NIAID · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Brian D Evavold · 2022 to 2026
$3.1MIn vivo studies of megakaryocyte microRNAs regulating platelet number and integrin activationR01HL141424 · NHLBI · UNIVERSITY OF UTAH · PI BRAY, PAUL F. · 2018 to 2021
$2.5MTranslational Control of Megakaryocyte and Platelet Function in SepsisR01HL142804 · NHLBI · UNIVERSITY OF UTAH · PI RONDINA, MATTHEW THOMAS · 2018 to 2021
$1.9MCONTROL OF ADAPTIVE IMMUNITY BY ACTIN-REGULATORY PROTEINSR01AI104732 · NIAID · WASHINGTON UNIVERSITY · PI MORLEY, SHARON CELESTE · 2014 to 2018
$1.9MPlatelet Immune Responses in Aging and InfluenzaR01AG048022 · NIA · UNIVERSITY OF UTAH · PI RONDINA, MATTHEW THOMAS · 2014 to 2018
$1.8MPlatelet-Leukocyte Interactions in SepsisK24HL155856 · NHLBI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI RONDINA, MATTHEW THOMAS · 2021 to 2025
$606kNovel Regulatory Mechanisms of Inflammation-Induced ThrombosisR56AG059877 · NIA · UNIVERSITY OF UTAH · PI RONDINA, MATTHEW THOMAS · 2018 to 2018
$381kPlatelet Reprogramming During InflammationI01CX001696 · VA · VA SALT LAKE CITY HEALTHCARE SYSTEM · PI Matthew Thomas Rondina · 2018 to 2026
–American Heart Association-American Stroke Association 906231American Heart Association-American Stroke Association 938717CSRD VA I01 CX001696NCI NIH HHS P30 CA042014NHLBI NIH HHS K24 HL155856NHLBI NIH HHS R01 HL130541NHLBI NIH HHS R01 HL141424NHLBI NIH HHS R01 HL142804NIAID NIH HHS R01 AI104732NIAID NIH HHS R01 AI169835NIA NIH HHS R01 AG048022NIA NIH HHS R56 AG059877
Abstract
PubMed holds no abstract for this paper.
Indexed as
ActinsMegakaryocytesHumansMembrane GlycoproteinsMicrofilament ProteinsPhosphoproteinsActinsMembrane GlycoproteinsMicrofilament ProteinsPhosphoproteinsplastin
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.