Evidence map›Paper›PMID 37439202›Full record

ArticleRenal failure2023

Cancer before and after the start of hemodialysis and association with mortality - an Eastern-European multicenter study.

Florica Gadalean, Mircea Ciorcan, Adrian Apostol, Oana Schiller, Viviana Ivan, Ligia Petrica, Flaviu Bob, Oana Milas, Anca Simulescu, Mihaela Glavan and 4 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Renal failure, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 4 countries.

Florica GadaleanDepartment of Internal Medicine II, Division of Nephrology, "Victor Babeș" University of Medicine and Pharmacy Timisoara, Timișoara, Romania.
Mircea CiorcanDepartment of Internal Medicine, Division of Practical Clinical Skills, "Victor Babeș" University of Medicine and Pharmacy Timisoara, Timișoara, Romania.
Adrian ApostolCentre for Molecular Research in Nephrology and Vascular Disease, "Victor Babeș" University of Medicine and Pharmacy, Timișoara, Romania.
Oana SchillerAvitum BBraun, Timisoara, Romania.
Viviana IvanCentre for Molecular Research in Nephrology and Vascular Disease, "Victor Babeș" University of Medicine and Pharmacy, Timișoara, Romania.
Ligia PetricaDepartment of Internal Medicine II, Division of Nephrology, "Victor Babeș" University of Medicine and Pharmacy Timisoara, Timișoara, Romania.
Flaviu BobDepartment of Internal Medicine II, Division of Nephrology, "Victor Babeș" University of Medicine and Pharmacy Timisoara, Timișoara, Romania.
Oana MilasDepartment of Internal Medicine II, Division of Nephrology, "Victor Babeș" University of Medicine and Pharmacy Timisoara, Timișoara, Romania.
Anca SimulescuDepartment of Internal Medicine II, Division of Nephrology, "Victor Babeș" University of Medicine and Pharmacy Timisoara, Timișoara, Romania.
Mihaela GlavanDepartment of Internal Medicine II, Division of Nephrology, "Victor Babeș" University of Medicine and Pharmacy Timisoara, Timișoara, Romania.
Florina ParvCentre for Molecular Research in Nephrology and Vascular Disease, "Victor Babeș" University of Medicine and Pharmacy, Timișoara, Romania.
Bogdan TimarCounty Emergency Hospital Timisoara, Timișoara, Romania.
Romulus TimarCounty Emergency Hospital Timisoara, Timișoara, Romania.
Adalbert SchillerDepartment of Internal Medicine II, Division of Nephrology, "Victor Babeș" University of Medicine and Pharmacy Timisoara, Timișoara, Romania.
Victor Babeș University of Medicine and Pharmacy Timișoara · ROCounty Hospital · GBAssociation Vinçotte Nuclear · BECognitive Research (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEast-European data on cancer in patients undergoing hemodialysis (HD) are scarce. This study aimed to assess the pattern of cancer and related mortality in patients with end-stage kidney disease (ESKD) undergoing HD.

methodsRetrospectively analyzing data from 7 HD centers, this study examined 1377 incident HD patients divided into three groups: no-cancers (NoC), cancers that occurred prior to HD initiation (CPI) and de novo cancer developed after HD initiation (DNC). Mortality risk and survival trends within groups were analyzed using Cox regression and Kaplan-Meier methods.

resultsIn the cohort, 89.46% of the patients had no cancer (NoC group), 3.63% had cancer before (CPI group), and 6.89% had cancer after HD initiation (DNC group). The mean time from HD initiation to DNC diagnosis was 1 [2.75] years. Older age was associated with a higher risk of developing DNC (

conclusionsEast-European ESKD patients undergoing HD have a high incidence of de novo cancers whose primary cancer sites are the digestive and urinary tracts. Almost half of the HD patients with CPI have hematologic and digestive tract cancers. Age and CTIN were associated with cancer risk. Cancer is an independent risk factor for all-cause mortality in patients undergoing hemodialysis (HD).

Indexed as

Kidney Failure, ChronicNeoplasmsNephritis, InterstitialHumansRenal DialysisRetrospective StudiesCancerEast European multicenter studyend-stage kidney diseasehemodialysis patientsmortalityrisk

Identifiers

PMID37439202
PMCPMC10348028
OpenAlexW4384120646

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.