ArticleClinical and experimental emergency medicine2023
Hemodynamic management of septic shock: beyond the Surviving Sepsis Campaign guidelines.
Article in Clinical and experimental emergency medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- Red Blood Cell Transfusion Beyond Restrictive Thresholds in Patients With Septic Shock and an Elevated Lactate Level: A Multicenter Observational Study.Journal of Korean medical science · 2026Observational
- Comparison of non-invasive strategies to drive fluid resuscitation in sepsis or septic shock: a meta-analysis of RCTs.Internal and emergency medicine · 2025Review
- Impact of diastolic blood pressure time under range on mortality and acute kidney injury in septic patients: a retrospective cohort study.BMC anesthesiology · 2025Article
- From Fluid Responsiveness to Prognosis: The Emerging Role of Point-of-Care Echocardiography in Sepsis.Diagnostics (Basel, Switzerland) · 2025Review
- Prognostic Value of the AST/ALT Ratio in Patients with Septic Shock: A Prospective, Multicenter, Registry-Based Observational Study.Diagnostics (Basel, Switzerland) · 2025Article
- Using machine learning techniques for early prediction of tracheal intubation in patients with septic shock: a multi-center study in South Korea.Acute and critical care · 2025Article
- Comparison between norepinephrine plus epinephrine and norepinephrine plus vasopressin after return of spontaneous circulation in patients with out-of-hospital cardiac arrest.Scientific reports · 2025Observational
- Urinary biomarkers for diagnosing acute kidney injury in sepsis in the emergency department.Heliyon · 2025Article
- Assessment of organ failure in sepsis patients in the emergency department: clinical evaluation, Sequential Organ Failure Assessment (SOFA) score, and future perspectives.Clinical and experimental emergency medicine · 2024Article
- Augmented renal clearance in neurocritical patients: An epidemiological investigation and risk-factor analysis.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024Article
- PiCCO or Cardiac Ultrasound? Which Is Better for Hemodynamic Monitoring in ICU?Medicina (Kaunas, Lithuania) · 2024Review
- Diagnostic Accuracy of Plasma Renin Concentration and Renin Activity in Predicting Mortality and Kidney Outcomes in Patients With Septic Shock and Hypoperfusion or Hypotension: A Multicenter, Prospective, Observational Study.Annals of laboratory medicine · 2024Observational
- Early Mortality Stratification with Serum Albumin and the Sequential Organ Failure Assessment Score at Emergency Department Admission in Septic Shock Patients.Life (Basel, Switzerland) · 2024Article
- The mortality of patients with sepsis increases in the first month of a new academic year.Clinical and experimental emergency medicine · 2024Article
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Corrections and comments
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Authors and funding
9 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the Surviving Sepsis Campaign guidelines provide standardized and generalized guidance, they are less individualized. This review focuses on recent updates in the hemodynamic management of septic shock. Monitoring and intervention for septic shock should be personalized according to the phase of shock. In the salvage phase, fluid resuscitation and vasopressors should be given to provide life-saving tissue perfusion. During the optimization phase, tissue perfusion should be optimized. In the stabilization and de-escalation phases, minimal fluid infusion and safe fluid removal should be performed, respectively, while preserving organ perfusion. There is controversy surrounding the use of restrictive versus liberal fluid strategies after initial resuscitation. Fluid administration after initial resuscitation should depend upon the patient's fluid responsiveness and requires individualized management. A number of dynamic tests have been proposed to monitor fluid responsiveness, which can help clinicians decide whether to give fluid or not. The optimal timing for the initiation of vasopressor agents is unknown. Recent data suggest that early vasopressor initiation should be considered. Inotropes can be considered in patients with decreased cardiac contractility associated with impaired tissue perfusion despite adequate volume status and arterial blood pressure. Venoarterial extracorporeal membrane oxygenation should be considered for refractory septic shock with severe cardiac systolic dysfunction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.