ArticleJournal of cachexia, sarcopenia and muscle2023
Analysis of the rate of force development reveals high neuromuscular fatigability in elderly patients with chronic kidney disease.
Article in Journal of cachexia, sarcopenia and muscle, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Pooled it
- An integrated model of rapid torque production: neuromuscular adaptations under fatigue after strength training.European journal of applied physiology · 2026Article
- Muscle Strength Profiles According to Kidney Dysfunction and Anemia Status in Korean Adults Aged ≥40 Years: A Nationwide Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Peak oxygen consumption is positively associated with estimates of oxygen extraction and microvascular blood volume in veterans with chronic kidney disease.American journal of physiology. Renal physiology · 2026Article
- Insights into Neuromuscular Function in Older Adults from Functional Data Analysis of Time-Dependent Handgrip Strength Curves.Bioengineering (Basel, Switzerland) · 2026Article
- The ageing microenvironment in sarcopenia: early alterations and targeted therapeutic strategies.Frontiers in immunology · 2026Review
- Quality matters: chronic kidney disease progression is associated with reduced muscle strength independently of changes in skeletal muscle mass: an observational study.Clinical kidney journal · 2025Article
- Low muscle strength and self-reported fatigue in patients on hemodialysis: findings from the SARC-HD study.Frontiers in nutrition · 2025Article
- Reliability and Validity of the Rate of Force Development for Quadriceps in Older Patients with Cardiovascular Disease.Journal of clinical medicine · 2024Article
- Article
- Does Obesity Affect the Rate of Force Development in Plantar Flexor Muscles among Older Adults?Sports (Basel, Switzerland) · 2024Article
- Exercise for patients with chronic kidney disease: from cells to systems to function.American journal of physiology. Renal physiology · 2024Review
- Analysis of the rate of force development reveals high neuromuscular fatigability in elderly patients with chronic kidney disease.Journal of cachexia, sarcopenia and muscle · 2023Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundChronic kidney disease (CKD) induces muscle wasting and a reduction in the maximum voluntary force (MVF). Little is known about the neuromuscular fatigability in CKD patients, defined as the reduction of muscle force capacities during exercise. Neuromuscular fatigability is a crucial physical parameter of the daily living. The quantification of explosive force has been shown to be a sensitive means to assess neuromuscular fatigability. Thus, our study used explosive force estimates to assess neuromuscular fatigability in elderly CKD patients.
methodsInclusion criteria for CKD patients were age ≥ 60 years old and glomerular filtration rate (GFR) < 45 mL/min/1.73 m
resultsThe cohort of 159 individuals had a median age of 69 (9
conclusionsOur study is the first to show that CKD patients have higher fatigability than controls, which may be associated with an impaired motor-unit recruitment, highlighting a neural drive disturbance with CKD. Further studies are needed to confirm these findings.
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