Evidence map›Paper›PMID 37438937›Full record

ArticleClinical and experimental dental research2023

Effects of aerosols from heated tobacco products with flavors on the discoloration of bovine tooth enamel.

Takeshi Kurachi, Shinnosuke Chuman, Takuya Suzuki, Terushige Kubota, Shinkichi Ishikawa

Abstract read
In one paragraph

Article in Clinical and experimental dental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Takeshi KurachiScientific Product Assessment Center, R&D Group, Japan Tobacco Inc., Yokohama, Kanagawa, Japan.ORCID 0000-0002-0572-0221
Shinnosuke ChumanScientific Product Assessment Center, R&D Group, Japan Tobacco Inc., Yokohama, Kanagawa, Japan.
Takuya SuzukiScientific and Regulatory Affairs, JT International SA, Geneva, Switzerland.
Terushige KubotaScientific and Regulatory Affairs, Japan Tobacco Inc., Tokyo, Japan.
Shinkichi IshikawaScientific Product Assessment Center, R&D Group, Japan Tobacco Inc., Yokohama, Kanagawa, Japan.ORCID 0000-0001-9501-6096

Funding

Japan Tobacco Inc. (JT) and JT International SA (JTI)
6 · The paper itself

Abstract

objectivesThis in vitro study assessed the potential of tooth discoloration by aerosols generated from three heated tobacco products (HTPs) with different specifications: in-direct heating tobacco system platform 1.0a (IT1.0a), in-direct heating tobacco system platform 2.0a (IT2.0a), and direct heating tobacco system platform 3.0a (DT3.0a). In addition, three flavor types (regular, menthol, and berry menthol) were selected for each HTP to characterize the effect of flavor types on tooth discoloration. MATERIAL AND

methodsSix bovine tooth samples were exposed directly to aerosols generated from one pack of each HTP: 350 puffs for IT1.0a, 325 puffs for IT2.0a, and 220 puffs for DT3.0a. Six bovine tooth samples were also exposed to air (350 puffs) and smoke generated from one pack of cigarettes (160 puffs) as negative and positive controls, respectively. The color of each tooth sample was measured before and after exposure. The overall color changes were assessed using overall color differences (ΔE) calculated according to the Commission International de I'Eclairage color system. A one-way analysis of variance followed by Tukey's post hoc test was used to compare ΔE among bovine tooth samples exposed to air, cigarette smoke, and aerosols generated from each HTP.

resultsΔE values for tooth samples exposed to air and aerosols generated from the three HTPs (IT1.0a, IT2.0a, and DT3.0a) were significantly lower than ΔE value for tooth samples exposed to cigarette smoke. ΔE values obtained with DT3.0a were significantly higher than those obtained with air-exposed control samples. However, ΔE values obtained with IT1.0a and IT2.0a were not significantly different from that obtained with air-exposed control samples. No HTPs showed significant differences in ΔE values among the three flavor types.

conclusionsThis study showed that HTP aerosols reduce tooth discoloration potential compared with cigarette smoke, regardless of flavor types, and the tooth discoloration potential of the product may depend on product specifications.

Indexed as

Tobacco ProductsTooth DiscolorationAerosolsAnimalsCattleDental EnamelMentholAerosolsMentholdental enamelin vitro techniquessmokingtooth discoloration

Identifiers

PMID37438937
PMCPMC10728517

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.