Evidence map›Paper›PMID 37438779›Full record

ArticleImplementation science communications2023

Comparison of methods to engage diverse stakeholder populations in prioritizing PrEP implementation strategies for testing in resource-limited settings: a cross-sectional study.

Sarah Hicks, Felix Abuna, Ben Odhiambo, Julia C Dettinger, Nancy Ngumbau, Laurén Gómez, Joseph Sila, George Oketch, Enock Sifuna, Bryan J Weiner and 3 more

Abstract read
In one paragraph

Article in Implementation science communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sarah HicksDepartment of Epidemiology, University of Washington, Seattle, WA, USA. smd722@uw.edu.ORCID http://orcid.org/0000-0001-9323-3214
Felix AbunaKenyatta National Hospital, Nairobi, Kenya.
Ben OdhiamboKenyatta National Hospital, Nairobi, Kenya.
Julia C DettingerDepartment of Global Health, University of Washington, Seattle, WA, USA.
Nancy NgumbauKenyatta National Hospital, Nairobi, Kenya.
Laurén GómezDepartment of Global Health, University of Washington, Seattle, WA, USA.
Joseph SilaKenyatta National Hospital, Nairobi, Kenya.
George OketchKenyatta National Hospital, Nairobi, Kenya.
Enock SifunaKenyatta National Hospital, Nairobi, Kenya.
Bryan J WeinerDepartment of Global Health, University of Washington, Seattle, WA, USA.
Grace C John-StewartDepartment of Epidemiology, University of Washington, Seattle, WA, USA.
John KinuthiaKenyatta National Hospital, Nairobi, Kenya.
Anjuli D WagnerDepartment of Global Health, University of Washington, Seattle, WA, USA.

Funding

University of Washington Developmental AIDS Research Center for Mental Health (UW ARCH)P30MH123248 · NIMH · UNIVERSITY OF WASHINGTON · PI SIMONI, JANE M. · 2021 to 2024
$5.8M
Testing implementation strategies to improve delivery of PrEP for pregnant and postpartum women in KenyaK01MH121124 · NIMH · UNIVERSITY OF WASHINGTON · PI WAGNER, ANJULI DAWN · 2019 to 2023
$835k
NIH HHS K01MH121124NIH HHS R01 HD094630-03S1NIMH NIH HHS K01 MH121124NIMH NIH HHS P30 MH123248
6 · The paper itself

Abstract

backgroundThere is a lack of consensus about how to prioritize potential implementation strategies for HIV pre-exposure prophylaxis (PrEP) delivery. We compared several prioritization methods for their agreement and pragmatism in practice in a resource-limited setting.

methodsWe engaged diverse stakeholders with clinical PrEP delivery and PrEP decision-making experience across 55 facilities in Kenya to prioritize 16 PrEP delivery strategies. We compared four strategy prioritization methods: (1) "past experience surveys" with experienced practitioners reflecting on implementation experience (N = 182); (2 and 3) "pre- and post-small-group ranking" surveys before and after group discussion (N = 44 and 40); (4) "go-zone" quadrant plots of perceived effectiveness vs feasibility. Kendall's correlation analysis was used to compare strategy prioritization using the four methods. Additionally, participants were requested to group strategies into three bundles with up to four strategies/bundle by phone and online survey.

resultsThe strategy ranking correlation was strongest between the pre- and post-small-group rankings (Tau: 0.648; p < 0.001). There was moderate correlation between go-zone plots and post-small-group rankings (Tau: 0.363; p = 0.079) and between past-experience surveys and post-small-group rankings (Tau: 0.385; p = 0.062). For strategy bundling, participants primarily chose bundles of strategies in the order in which they were listed, reflecting option ordering bias. Neither the phone nor online approach was effective in selecting strategy bundles. Participants agreed that the strategy ranking activities conducted during the workshop were useful in prioritizing a final set of strategies.

conclusionsBoth experienced and inexperienced stakeholder participants' strategy rankings tended to prioritize strategies perceived as feasible. Small group discussions focused on feasibility and effectiveness revealed moderately different priorities than individual rankings. The strategy bundling approach, though less time- and resource-intensive, was not effective. Future research should further compare the relative effectiveness and pragmatism of methodologies to prioritize implementation strategies.

Indexed as

Implementation determinantsImplementation strategyNominal group techniquePrioritization

Identifiers

PMID37438779
PMCPMC10337117

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.