ArticleRespiratory research2023
Oral bacterial composition associated with lung function and lung inflammation in a community-based Norwegian population.
Article in Respiratory research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Impact of Electronic Cigarette Use on the Oral Microbiota: A Systematic Review.Journal of clinical periodontology · 2026Pooled it
- Role of oral bacteria composition and functional gene profiles in respiratory diseases.BMJ open respiratory research · 2026Article
- Characteristics of Respiratory Microbiome in COPD-A Literature Review.Advances in respiratory medicine · 2026Review
- Gingipain proteases from the bacteriumProceedings of the National Academy of Sciences of the United States of America · 2026Article
- NLRP3 inflammasomes at the ARDS-cancer interface: mechanisms and translational hypotheses.Frontiers in immunology · 2026Review
- Impact of electronic cigarette use on the oral microbiome: a protocol for a systematic review of clinical studies.Systematic reviews · 2025Article
- Oral microbiota and respiratory diseases: advances and perspectives.Clinical microbiology reviews · 2025Review
- Chronic airway inflammatory diseases and e-cigarette use: a review of health risks and mechanisms.European journal of medical research · 2025Review
- Longitudinal impact of oral bacteria and endotoxin on lung function.European clinical respiratory journal · 2025Article
- Oropharyngeal detection of specific gut-derived Enterobacterales is associated with increased respiratory infection risk in older adults.Frontiers in aging · 2025Article
- Fractional exhaled nitric oxide distribution and its relevant factors in the general adult population and its healthy subpopulation.The journal of allergy and clinical immunology. Global · 2024Article
- Article
- The Lung Microbiome.Journal of immunology (Baltimore, Md. : 1950) · 2024Review
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundThe oral cavity is the gateway to the bacteria community in the lung. Disruption of the symbiotic balance of the oral microbiota has been associated with respiratory diseases. However, little is known about the relationship between oral bacteria and respiratory outcomes in the general population. We aimed to describe the associations between oral bacteria, lung function, and lung inflammation in a community-based population.
methodsOral (gingival) samples were collected concurrently with spirometry tests in 477 adults (47% males, median age 28 years) from the RHINESSA study in Bergen, Norway. Bacterial DNA from the 16S rRNA gene from gingival fluid were sequenced by Illumina
resultsThe abundance of the genera Clostridiales, Achromobacter, Moraxella, Flavitalea and Helicobacter were significantly different among those with low FEV
conclusionOral bacterial composition was significantly different for those with low FEV or FVC as compared to those with normal lung function equal to or higher than LLN. Differential bacterial composition was also observed for elevated FeNO levels.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.