Evidence map›Paper›PMID 37438661›Full record

Trial reportAesthetic plastic surgery2024

Comparing the Effectiveness of Betamethasone and Triamcinolone Acetonide in Multimodal Cocktail Intercostal Injection for Chest Pain After Harvesting Costal Cartilage: A Prospective, Double-Blind, Randomized Controlled Study.

Xin Wang, Wenfang Dong, Zhen Song, Huan Wang, Jianjun You, Ruobing Zheng, Yihao Xu, Xulong Zhang, Junsheng Guo, Le Tian and 1 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Aesthetic plastic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Xin WangDepartment of Rhinoplasty, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 33, Badachu Road, Shijingshan, Beijing, 100730, People's Republic of China.
Wenfang Dong *Department of Plastic and Reconstructive Surgery, Peking University third Hospital, 49 North Huayuan Road, Beijing, 100191, People's Republic of China.
Zhen Song *Department of Rhinoplasty, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 33, Badachu Road, Shijingshan, Beijing, 100730, People's Republic of China.
Huan WangDepartment of Rhinoplasty, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 33, Badachu Road, Shijingshan, Beijing, 100730, People's Republic of China.
Jianjun YouDepartment of Rhinoplasty, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 33, Badachu Road, Shijingshan, Beijing, 100730, People's Republic of China.
Ruobing ZhengDepartment of Rhinoplasty, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 33, Badachu Road, Shijingshan, Beijing, 100730, People's Republic of China.
Yihao XuDepartment of Rhinoplasty, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 33, Badachu Road, Shijingshan, Beijing, 100730, People's Republic of China.
Xulong ZhangDepartment of Rhinoplasty, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 33, Badachu Road, Shijingshan, Beijing, 100730, People's Republic of China.
Junsheng GuoDepartment of Rhinoplasty, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 33, Badachu Road, Shijingshan, Beijing, 100730, People's Republic of China.
Le TianDepartment of Rhinoplasty, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 33, Badachu Road, Shijingshan, Beijing, 100730, People's Republic of China.
Fei FanDepartment of Rhinoplasty, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 33, Badachu Road, Shijingshan, Beijing, 100730, People's Republic of China. fanfei@psh.pumc.edu.cn.ORCID 0000-0002-6725-6305
Chinese Academy of Medical Sciences & Peking Union Medical College · CNPeking University · CN

Funding

The Foundation of the Chinese Academy of Medical Sciences-Plastic Surgery Hospital 3060120043
6 · The paper itself

Abstract

backgroundThere has been no previous study on the availability of different glucocorticoid varieties used in the multimodal cocktail for harvesting autologous costal cartilage. This randomized controlled trial (RCT) was to compare the significance and complications of betamethasone and triamcinolone acetonide as a component of the cocktail for harvesting costal cartilage in patients. MATERIALS AND

methodsThe patients were randomized to two groups. The group A used multimodal cocktail: ropivacaine, parecoxib sodium, epinephrine, and triamcinolone acetonide; group B used multimodal cocktail: ropivacaine, parecoxib sodium, epinephrine, and betamethasone. The primary outcomes were chest pain after surgery evaluated with a visual analog scale (VAS). The secondary outcomes evaluated the quality of recovery. The tertiary outcomes included rescue analgesic consumption, the first feeding time and the time to the first ambulation, and duration of hospital stay.

resultsThe VAS scores between the two groups was not considered clinically significant, but the groups achieved a VAS score of 3 or less. However, the time until the first rescue analgesia and the number were significantly longer and smaller for group A. Additionally, there were no significant differences between the two groups in the duration of hospital stay, first feeding time, the quality of recovery, and the first ambulation time.

conclusionAdding corticosteroids into the multimodal cocktails could improve pain relief after costal cartilage harvest. And the efficacy of Triamcinolone acetonide was better than betamethasone. LEVEL OF EVIDENCE II: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Costal CartilageTriamcinolone AcetonideBetamethasoneChest PainDouble-Blind MethodEpinephrineHumansPostoperative PainRopivacaineBetamethasoneEpinephrineRopivacaineTriamcinolone AcetonideBetamethasoneCostal cartilagePainSteroidsTriamcinolone acetonide

Identifiers

PMID37438661
OpenAlexW4384071739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.