ArticleScientific reports2023
The influence of sac centreline on saccular aneurysm rupture: computational study.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Hemodynamic Alterations Associated with Varying Aneurysm Sizes in the Aortic Arch.Bioengineering (Basel, Switzerland) · 2026Article
- Hemodynamic response to stent-induced aneurysm deformation in patient-specific internal carotid artery cases: A computational study.Scientific reports · 2025Article
- Use of proper orthogonal decomposition and machine learning for efficient blood flow prediction in cerebral saccular aneurysms.Scientific reports · 2025Article
- Hemodynamic assessment of rupture risk during growth stages in middle cerebral artery aneurysms treated with coiling.Scientific reports · 2025Article
- A predictive surrogate model of blood haemodynamics for patient-specific carotid artery stenosis.Journal of the Royal Society, Interface · 2025Article
- In Vivo Deformation of the Human Basilar Artery.Annals of biomedical engineering · 2025Article
- Hemodynamic evaluation of endovascular techniques of stenting and coiling for the treatment of internal carotid artery aneurysm: a computational study.Scientific reports · 2024Article
- Enhancing understanding of stent-induced deformation in MCA aneurysms: a hemodynamic study.Scientific reports · 2024Article
- Influence of physiological conditions on hemodynamics of internal carotid artery aneurysms.Scientific reports · 2024Article
- Hemodynamics study of anterior cerebral artery with different sac centerline lengths for rupture risk assessment.Scientific reports · 2024Article
- Numerical simulation of cellular blood flow in curved micro-vessels with saccular aneurysms: Effect of curvature degree and hematocrit level.Biomicrofluidics · 2024Article
- Hemodynamic study of the ICA aneurysm evolution to attain the cerebral aneurysm rupture risk.Scientific reports · 2024Article
- Usage of computational method for hemodynamic analysis of intracranial aneurysm rupture risk in different geometrical aspects.Scientific reports · 2023Article
- Influence of parent vessel feature on the risk of internal carotid artery aneurysm rupture via computational method.Scientific reports · 2023Article
- Computational and statistical analyses of blood hemodynamic inside cerebral aneurysms for treatment evaluation of endovascular coiling.Scientific reports · 2023Article
- Impacts of morphology parameters on the risk of rupture in intracranial aneurysms: statistical and computational analyses.Scientific reports · 2023Article
- Analysis of the effects of stent-induced deformation on the hemodynamics of MCA aneurysms.Scientific reports · 2023Article
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The geometric characteristics of a saccular aneurysm play a crucial role in its rupturing. This article thoroughly investigates the impact of the sac centerline on aneurysm rupture, with a focus on identifying significant factors related to rupture at different time intervals. The study employs comprehensive computational simulations of six models of the ICA with varying coiling porosities and blood HCTs, using CFD analysis to examine WSS, OSI, pressure, and velocity within the saccular aneurysm for different sac centerlines. The results indicate that higher blood HCT levels lead to increased WSS and pressure values on the aneurysm wall, while OSI and mean velocity decrease. The study also reveals that coiling techniques can significantly reduce the risk of rupture, as decreasing coil porosity (increasing coil permeability) increases OSI and pressure while decreasing WSS and blood velocity within the aneurysm sac.
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