Evidence map›Paper›PMID 37438085›Full record

ArticleLife science alliance2023

Transcriptome-wide RNA binding analysis of C9orf72 poly(PR) dipeptides.

Rubika Balendra, Igor Ruiz de Los Mozos, Hana M Odeh, Idoia Glaria, Carmelo Milioto, Katherine M Wilson, Agnieszka M Ule, Martina Hallegger, Laura Masino, Stephen Martin and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life science alliance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 3 countries.

Rubika BalendraUK Dementia Research Institute at UCL, London, UK.ORCID https://orcid.org/0000-0002-6817-2365
Igor Ruiz de Los MozosThe Francis Crick Institute, London, UK.ORCID https://orcid.org/0000-0003-4097-6422
Hana M OdehDepartment of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Idoia GlariaUK Dementia Research Institute at UCL, London, UK.ORCID https://orcid.org/0000-0003-4556-489X
Carmelo MiliotoUK Dementia Research Institute at UCL, London, UK.ORCID https://orcid.org/0000-0002-3844-0728
Katherine M WilsonUK Dementia Research Institute at UCL, London, UK.
Agnieszka M UleDepartment of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London, UK.
Martina HalleggerThe Francis Crick Institute, London, UK.
Laura MasinoStructural Biology Science Technology Platform, The Francis Crick Institute, London, UK.
Stephen MartinStructural Biology Science Technology Platform, The Francis Crick Institute, London, UK.
Rickie PataniThe Francis Crick Institute, London, UK.
James ShorterDepartment of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.ORCID https://orcid.org/0000-0001-5269-8533
Jernej UleThe Francis Crick Institute, London, UK jernej.ule@kcl.ac.uk.ORCID https://orcid.org/0000-0002-2452-4277
Adrian M IsaacsUK Dementia Research Institute at UCL, London, UK a.isaacs@ucl.ac.uk.ORCID https://orcid.org/0000-0002-6820-5534
UK Dementia Research Institute · GBThe Francis Crick Institute · GBUniversity of Pennsylvania · USGovernment of Spain · ESKing's College London · GBNational Hospital for Neurology and Neurosurgery · GB

Funding

Medical Research Council MR/S006591/1Wellcome TrustWellcome Trust 107196/Z/14/Z
6 · The paper itself

Abstract

An intronic GGGGCC repeat expansion in

Indexed as

Gene Expression ProfilingTranscriptomeC9orf72 ProteinDipeptidesHumansPoly ARNAC9orf72 ProteinC9orf72 protein, humanDipeptidesPoly ARNA

Identifiers

PMID37438085
PMCPMC10338859
OpenAlexW4384028750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.