Evidence map›Paper›PMID 37437226›Full record

ArticleJCO oncology practice2023

Integrated Radiology, Pathology, and Pharmacy Program to Accelerate Access to Osimertinib.

Ibiayi Dagogo-Jack, Amanda Manoogian, Nicholas Jessop, N Zeke Georgantas, Florian J Fintelmann, Alexander Farahani, Subba R Digumarthy, Melissa C Price, Erik E Folch, Colleen M Keyes and 12 more

Open access · greenAbstract read
In one paragraph

Article in JCO oncology practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 3 institutions in 1 country.

Ibiayi Dagogo-JackMassachusetts General Hospital Cancer Center, Boston, MA.ORCID 0000-0003-0781-9257
Amanda ManoogianPartners Health Specialty Pharmacy, Boston, MA.
Nicholas JessopCenter for Integrated Diagnostics, Massachusetts General Hospital, Boston, MA.
N Zeke GeorgantasCenter for Integrated Diagnostics, Massachusetts General Hospital, Boston, MA.
Florian J FintelmannHarvard Medical School, Boston, MA.ORCID 0000-0002-0119-3903
Alexander FarahaniCenter for Integrated Diagnostics, Massachusetts General Hospital, Boston, MA.
Subba R DigumarthyHarvard Medical School, Boston, MA.
Melissa C PriceHarvard Medical School, Boston, MA.
Erik E FolchHarvard Medical School, Boston, MA.
Colleen M KeyesHarvard Medical School, Boston, MA.ORCID 0000-0001-7603-327X
Andrew DoMassachusetts General Hospital Cancer Center, Boston, MA.ORCID 0000-0002-5782-5818
Jennifer L PetersonMassachusetts General Hospital Cancer Center, Boston, MA.
Mari Mino-KenudsonHarvard Medical School, Boston, MA.ORCID 0000-0002-9092-2265
Martha PitmanHarvard Medical School, Boston, MA.
Miguel RiveraHarvard Medical School, Boston, MA.ORCID 0000-0002-3636-2113
Valentina NardiHarvard Medical School, Boston, MA.
Dora Dias-SantagataHarvard Medical School, Boston, MA.
Long P LeCenter for Integrated Diagnostics, Massachusetts General Hospital, Boston, MA.
Anthony John IafrateHarvard Medical School, Boston, MA.
Rebecca S HeistMassachusetts General Hospital Cancer Center, Boston, MA.ORCID 0000-0002-7397-2009
Lauren R RitterhouseHarvard Medical School, Boston, MA.
Jochen K LennerzHarvard Medical School, Boston, MA.ORCID 0000-0003-2434-4978
Harvard University · USMassachusetts General Hospital · USMass General Brigham · US

Funding

Illuminating the evolutionary history of colorectal cancer metastasis: basic principles and clinical applicationsR37CA225655 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI NAXEROVA, KAMILA · 2018 to 2024
$3.0M
NCI NIH HHS R37 CA225655
6 · The paper itself

Abstract

purposeTargeted therapy yields superior outcomes relative to genotype-agnostic therapy for patients with epidermal growth factor receptor (

methodsWe developed an

resultsBetween January 2020 and December 2021, 222 patients participated in the intervention. The median turnaround time from biopsy to EGFR results was 1 workday. Forty-nine (22%) tumors harbored

conclusionCombining radiology and pathology workflows with early parallel pharmacy engagement leads to a significant reduction in time to initiating osimertinib. Multidisciplinary integration programs are essential to maximize clinical utility of rapid testing.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsPharmacyRadiologyAcrylamidesAniline CompoundsErbB ReceptorsHumansIndolesPyrimidinesAcrylamidesAniline CompoundsErbB ReceptorsIndolesosimertinibPyrimidines

Identifiers

PMID37437226
PMCPMC10538938
OpenAlexW4384008071

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.