ArticlePloS one2023
The impact of angles of insonation on left and right ventricular global longitudinal strain estimation in fetal speckle tracking echocardiography.
Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Fetal Cardiac Function in Early Labour and Intrapartum Outcomes: A Prospective Observational Study.BJOG : an international journal of obstetrics and gynaecology · 2026Observational
- Fetal Cardiac Deformation in Persistent Left-Sided Superior Vena Cava and Suspected Coarctation of the Aorta.Pediatric cardiology · 2026Article
- Reproducibility of fetal global longitudinal strain measured with speckle tracking echocardiography using a fixed cardiac cycle.PloS one · 2026Article
- Inclusion of Speckle Tracking Echocardiography Analysis in the Management of Intrauterine Growth Restrictions-Literature Review and Case Reports.Journal of clinical medicine · 2025Review
- Evaluation of fetal cardiac morphology and function by fetal heart quantification technique in the normal second and third trimesters.Translational pediatrics · 2024Article
- Feasibility and reliability of fetal two dimensional speckle tracking echocardiography at 16 weeks gestational age: A pilot study.PloS one · 2024Article
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTwo-dimensional speckle tracking echocardiography has been considered an angle-independent modality. However, current literature is limited and inconclusive on the actual impact of angle of insonation on strain values. Therefore, the primary objective of this study was to assess the impact of angles of insonation on the estimation of fetal left ventricular and right ventricular global longitudinal strain. Secondarily, the impact of different definitions for angles of insonation was investigated in a sensitivity analysis.
methodsThis is a retrospective analysis of a prospective longitudinal cohort study with 124 healthy subjects. The analyses were based on the four-chamber view ultrasound clips taken between 18+0 and 21+6 weeks of gestation. Angles of insonation were categorized into three groups: up/down, oblique and perpendicular. The mean fetal left and right ventricular and global longitudinal strain values corresponding to these three groups were compared by an ANOVA test corrected for heteroscedasticity.
resultsFetal left and right ventricular global longitudinal strain values were not statistically different between the three angles of insonation (p-value >0.062 and >0.149, respectively). When applying another definition for angles of insonation in the sensitivity analysis, the mean left ventricular global longitudinal strain value was significantly decreased for the oblique compared to the up/down angle of insonation (p-value 0.041).
conclusionsThere is no evidence of a difference in fetal left and right ventricular global longitudinal strain between the different angles of insonation in fetal two-dimensional speckle tracking echocardiography.
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