Evidence map›Paper›PMID 37436770›Full record

ReviewClinical infectious diseases : an official publication of the Infectious Diseases Society of America2023

Global Landscape of Encephalitis: Key Priorities to Reduce Future Disease Burden.

Julia Granerod, Yun Huang, Nicholas W S Davies, Patricia C Sequeira, Victor Mwapasa, Priscilla Rupali, Benedict D Michael, Tom Solomon, Ava Easton

Open access · hybridAbstract readReview
In one paragraph

Review in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 4 countries.

Julia GranerodDepartment of Clinical Infection Microbiology and Immunology, Institute of Infection, Veterinary, and Ecological Science, University of Liverpool, Liverpool, United Kingdom.
Yun HuangDepartment of Clinical Infection Microbiology and Immunology, Institute of Infection, Veterinary, and Ecological Science, University of Liverpool, Liverpool, United Kingdom.
Nicholas W S DaviesDepartment of Neurology, Charing Cross Hospital, London, United Kingdom.
Patricia C SequeiraLaboratorio de Flavivirus, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Victor MwapasaUniversity of Malawi, College of Medicine, Blantyre, Malawi.
Priscilla RupaliDepartment of Infectious Diseases, Christian Medical College Vellore, Vellore, Tamil Nadu, India.
Benedict D MichaelDepartment of Clinical Infection Microbiology and Immunology, Institute of Infection, Veterinary, and Ecological Science, University of Liverpool, Liverpool, United Kingdom.
Tom SolomonDepartment of Clinical Infection Microbiology and Immunology, Institute of Infection, Veterinary, and Ecological Science, University of Liverpool, Liverpool, United Kingdom.
Ava EastonDepartment of Clinical Infection Microbiology and Immunology, Institute of Infection, Veterinary, and Ecological Science, University of Liverpool, Liverpool, United Kingdom.
Walton Centre · GBCharing Cross Hospital · GBChristian Medical College & Hospital · INEncephalitis Society · GBFundação Oswaldo Cruz · BRHealth Protection Research Unit in Emerging and Zoonotic Infections at University of Liverpool · GBUniversity of Liverpool · GBUniversity of Malawi · MW

Funding

Medical Research Council MC_PC_19059Medical Research Council MR/V007181/1Wellcome Trust
6 · The paper itself

Abstract

Encephalitis affects people across the lifespan, has high rates of mortality and morbidity, and results in significant neurological sequelae with long-term consequences to quality of life and wider society. The true incidence is currently unknown due to inaccurate reporting systems. The disease burden of encephalitis is unequally distributed across the globe being highest in low- and middle-income countries where resources are limited. Here countries often lack diagnostic testing, with poor access to essential treatments and neurological services, and limited surveillance and vaccination programs. Many types of encephalitis are vaccine preventable, whereas others are treatable with early diagnosis and appropriate management. In this viewpoint, we provide a narrative review of key aspects of diagnosis, surveillance, treatment, and prevention of encephalitis and highlight priorities for public health, clinical management, and research, to reduce the disease burden.

Indexed as

EncephalitisQuality of LifeCost of IllnessDisease ProgressionHumansIncidenceburdendiagnosisencephalitistreatmentvaccination

Identifiers

PMID37436770
PMCPMC10686956
OpenAlexW4383998439

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.