Evidence map›Paper›PMID 37436684›Full record

SynthesisJournal of racial and ethnic health disparities2024

The Association of Race and Ethnicity with Mortality in Pediatric Patients with Congenital Heart Disease: a Systematic Review.

Meredith Sooy-Mossey, Mirai Matsuura, Jordan E Ezekian, Jason L Williams, Grace S Lee, Kathleen Wood, Samantha Dizon, Samantha J Kaplan, Jennifer S Li, Victoria Parente

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of racial and ethnic health disparities, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. "AJP reports · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Meredith Sooy-MosseyDivision of Pediatric Cardiology, Department of Pediatrics, Duke University School of Medicine, 2301 Erwin Road, DUMC Box 3127, Durham, NC, 27710, USA. meredith.sooy@duke.edu.ORCID 0000-0003-3283-3341
Mirai MatsuuraDeparment of Pediatrics, Massachusetts General Hospital, Boston, MA, USA.
Jordan E EzekianDivision of Cardiology, Hospital for Sick Children, Toronto, Ontario, Canada.
Jason L WilliamsDivision of Pediatric Cardiology, Department of Pediatrics, Duke University School of Medicine, 2301 Erwin Road, DUMC Box 3127, Durham, NC, 27710, USA.
Grace S LeeDepartment of Pediatrics, Duke University School of Medicine, Durham, NC, USA.
Kathleen WoodDivision of Pediatric Cardiology, Department of Pediatrics, Duke University School of Medicine, 2301 Erwin Road, DUMC Box 3127, Durham, NC, 27710, USA.
Samantha DizonDivision of Cardiology, Columbia University Department of Medicine, New York, NY, USA.
Samantha J KaplanMedical Center Library and Archives, Duke University, Durham, NC, USA.
Jennifer S LiDivision of Pediatric Cardiology, Department of Pediatrics, Duke University School of Medicine, 2301 Erwin Road, DUMC Box 3127, Durham, NC, 27710, USA.
Victoria ParentePediatric Hospital Medicine, Duke University School of Medicine, Durham, NC, USA.

Funding

Research Project 3U54MD012530 · NIMHD · DUKE UNIVERSITY · PI JOHNSON, KIMBERLY S. · 2017 to 2022
$8.8M
Stimulating Access to Research in Residency (StARR) - NHLBIR38HL143612 · NHLBI · DUKE UNIVERSITY · PI Mai ElMallah, David H. Harpole · 2018 to 2026
$2.6M
NHLBI NIH HHS L40 HL170360NHLBI NIH HHS R38 HL143612NIMHD NIH HHS U54 MD012530
6 · The paper itself

Abstract

contextCongenital heart disease (CHD) is a common condition with high morbidity and mortality and is subject to racial and ethnic health disparities.

objectiveTo conduct a systematic review of the literature to identify differences in mortality in pediatric patients with CHD based on race and ethnicity. DATA SOURCES: Legacy PubMed (MEDLINE), Embase (Elsevier), and Scopus (Elsevier) STUDY SELECTION: English language articles conducted in the USA focused on mortality based on race and ethnicity in pediatric patients with CHD. DATA EXTRACTION: Two independent reviewers assessed studies for inclusion and performed data extraction and quality assessment. Data extraction included mortality based on patient race and ethnicity.

resultsThere were 5094 articles identified. After de-duplication, 2971 were screened for title and abstract content, and 45 were selected for full-text assessment. Thirty studies were included for data extraction. An additional 8 articles were identified on reference review and included in data extraction for a total of 38 included studies. Eighteen of 26 studies showed increased risk of mortality in non-Hispanic Black patients. Results were heterogenous in Hispanic patients with eleven studies of 24 showing an increased risk of mortality. Results for other races demonstrated mixed outcomes. LIMITATIONS: Study cohorts and definitions of race and ethnicity were heterogenous, and there was some overlap in national datasets used.

conclusionOverall, racial and ethnic disparities existed in the mortality of pediatric patients with CHD across a variety of mortality types, CHD lesions, and pediatric age ranges. Children of races and ethnicities other than non-Hispanic White generally had increased risk of mortality, with non-Hispanic Black children most consistently having the highest risk of mortality. Further investigation is needed into the underlying mechanisms of these disparities so interventions to reduce inequities in CHD outcomes can be implemented.

Indexed as

Heart Defects, CongenitalChildChild, PreschoolEthnicityHealth Status DisparitiesHispanic or LatinoHumansInfantRacial GroupsUnited StatesCongenital Heart DiseaseEthnicityHealth EquityMortalityRace

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.