Evidence map›Paper›PMID 37436657›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2023

Association between office visit intervals and long-term cardiovascular risk in hypertensive patients.

Duon Kim, Hyunmook Jeong, Suhyun Kim, Ho-Gyun Shin, Kyun-Ik Park, Seung-Pyo Lee, Hee-Sun Lee, Ju-Yeun Lee, Kwang-Il Kim, Si-Hyuck Kang and 10 more

Abstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Duon KimDepartment of Medicine, Seoul National University College of Medicine, Seoul, South Korea.
Hyunmook JeongBiomedical Research Institute, Seoul National University Hospital, Seoul, South Korea.
Suhyun KimTransdisciplinary Department of Medicine & Advanced Technology, Seoul National University Hospital, Seoul, South Korea.ORCID 0000-0002-9726-1949
Ho-Gyun ShinNational Evidence-based Healthcare Collaborating Agency (NECA), Seoul, South Korea.
Kyun-Ik ParkNational Evidence-based Healthcare Collaborating Agency (NECA), Seoul, South Korea.
Seung-Pyo LeeDepartment of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.
Hee-Sun LeeDepartment of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.
Ju-Yeun LeeCollege of Pharmacy, Seoul National University, Seoul, South Korea.
Kwang-Il KimDepartment of Internal Medicine, Seoul National University Bundang Hospital, Sungnam, South Korea.
Si-Hyuck KangDepartment of Internal Medicine, Seoul National University Bundang Hospital, Sungnam, South Korea.
Jang Hoon LeeDepartment of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, South Korea.ORCID 0000-0002-7101-0236
Se Yong JangDepartment of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, South Korea.
Ju-Hee LeeDivision of Cardiology, Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, South Korea.
Kye Hun KimDepartment of Cardiovascular Medicine, Chonnam National University Medical School/Hospital, Gwangju, South Korea.
Jae Yeong ChoDepartment of Cardiovascular Medicine, Chonnam National University Medical School/Hospital, Gwangju, South Korea.
Jae-Hyeong ParkDepartment of Internal Medicine, Chungnam National University College of Medicine, Daejeon, South Korea.
Sue K ParkDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, South Korea.
Seungyeon KimCollege of Pharmacy, Dankook University, Cheonan, South Korea.
Kwangsoo KimTransdisciplinary Department of Medicine & Advanced Technology, Seoul National University Hospital, Seoul, South Korea.
Hae-Young LeeDepartment of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.ORCID 0000-0002-9521-4102

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension is a chronic disease that requires long-term follow-up in many patients, however, optimal visit intervals are not well-established. This study aimed to evaluate the incidences of major cardiovascular events (MACEs) according to visit intervals. We analyzed data from 9894 hypertensive patients in the Korean Hypertension Cohort, which enrolled and followed up 11,043 patients for over 10 years. Participants were classified into five groups based on their median visit intervals (MVIs) during the 4-year period and MACEs were compared among the groups. The patients were divided into clinically relevant MVIs of one (1013; 10%), two (1299; 13%), three (2732; 28%), four (2355; 24%), and six months (2515; 25%). The median follow-up period was 5 years (range: 1745 ± 293 days). The longer visit interval groups did not have an increased cumulative incidence of MACE (12.9%, 11.8%, 6.7%, 5.9%, and 4%, respectively). In the Cox proportional hazards model, those in the longer MVI group had a smaller hazard ratio (HR) for MACEs or all-cause death: 1.77 (95% confidence interval [CI], 1.45-2.17), 1.7 (95% CI: 1.41-2.05), 0.90 (95% CI: 0.74-1.09) and 0.64 (95% CI: 0.52-0.79), respectively (Reference MVI group of 75-104 days). In conclusion, a follow-up visits with a longer interval of 3-6 months was not associated with an increased risk of MACE or all-cause death in hypertensive patients. Therefore, once medication adjustment is stabilized, a longer interval of 3-6 months is reasonable, reducing medical expenses without increasing the risk of cardiovascular outcomes.

Indexed as

Cardiovascular DiseasesHypertensionHeart Disease Risk FactorsHumansOffice VisitsRisk Factorscardiovascular eventhypertensionvisit intervals

Identifiers

PMID37436657
PMCPMC10423752

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.