Evidence map›Paper›PMID 37436644›Full record

ArticleInflammation2023

Cysteine-cysteine Chemokine Receptor Type 5 Plays a Critical Role in Exercise Performance by Regulating Mitochondrial Content in Skeletal Muscle.

Chien-Wei Chen, Luen-Kui Chen, Yi-Ting Chung, Shui-Yu Liu, Shuoh-Wen Chen, Yuan-I Chang, Po-Shiuan Hsieh, Chi-Chang Juan

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Chien-Wei ChenInternational Sport Science Master's Program, College of Human Development and Health, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.
Luen-Kui ChenInstitutes of Physiology, College of Medicine, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Li-Nong St., 112304, Taipei, Taiwan.
Yi-Ting ChungInstitutes of Physiology, College of Medicine, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Li-Nong St., 112304, Taipei, Taiwan.
Shui-Yu LiuInstitutes of Physiology, College of Medicine, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Li-Nong St., 112304, Taipei, Taiwan.
Shuoh-Wen ChenInstitutes of Physiology, College of Medicine, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Li-Nong St., 112304, Taipei, Taiwan.
Yuan-I ChangInstitutes of Physiology, College of Medicine, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Li-Nong St., 112304, Taipei, Taiwan.
Po-Shiuan HsiehDepartment of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan.
Chi-Chang JuanInstitutes of Physiology, College of Medicine, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Li-Nong St., 112304, Taipei, Taiwan. ccjuan@nycu.edu.tw.
National Yang Ming Chiao Tung University · TWNational Taipei University of Nursing and Health Science · TWTri-Service General Hospital · TW

Funding

National Science and Technology Council 110-2320-B-A49A-518, 111-2320-B-A49-039, and 110-2320-B227-001
6 · The paper itself

Abstract

Cysteine-cysteine chemokine receptor type 5 (CCR5) is thought to play an important role in the trafficking of lymphoid cells but has recently also been associated with AMPK signaling pathways that are implicated in energy metabolism in skeletal muscle. We hypothesized that genetic deletions of CCR5 would alter mitochondria content and exercise performance in mice. CCR5

Indexed as

CysteineTranscription FactorsAnimalsLigandsMiceMice, KnockoutMitochondriaMuscle, SkeletalPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPPAR gammaReceptors, ChemokineCysteineLigandsPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPPAR gammaReceptors, ChemokineTranscription FactorsCysteine-cysteine chemokine receptor type 5Exercise performanceMitochondrial complexMuscle atrophyMyosin heavy chain 7

Identifiers

PMID37436644
OpenAlexW4383999326

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.