Evidence map›Paper›PMID 37436568›Full record

ArticleJournal of general internal medicine2023

Racial and Ethnic Inequities in Buprenorphine and Methadone Utilization Among Reproductive-Age Women with Opioid Use Disorder: an Analysis of Multi-state Medicaid Claims in the USA.

Kevin Y Xu, Davida M Schiff, Hendrée E Jones, Caitlin E Martin, Jeannie C Kelly, Laura J Bierut, Ebony B Carter, Richard A Grucza

Open access · bronzeAbstract read
In one paragraph

Article in Journal of general internal medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

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  4. Exploring Preferences in Emergency Department Coordination of Opioid Use Disorder Treatment by Race and Ethnicity.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Kevin Y XuHealth and Behavior Research Center, Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA. xukeviny@wustl.edu.ORCID 0000-0001-6595-695X
Davida M SchiffDivision of General Academic Pediatrics, Mass General Hospital for Children, Boston, MA, USA.
Hendrée E JonesDepartment of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Caitlin E MartinDepartment of Obstetrics and Gynecology and VCU Institute for Drug and Alcohol Studies, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
Jeannie C KellyDivision of Maternal-Fetal Medicine and the Division of Clinical Research, Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, USA.
Laura J BierutHealth and Behavior Research Center, Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
Ebony B CarterDivision of Maternal-Fetal Medicine and the Division of Clinical Research, Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, USA.
Richard A GruczaDepartments of Family and Community Medicine and Health and Outcomes Research, St. Louis University, St. Louis, MO, USA.
Washington University in St. Louis · USBarnes-Jewish Hospital · USMassachusetts General Hospital · USSaint Louis University · USUniversity of North Carolina at Chapel Hill · USVirginia Commonwealth University · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Transdisciplinary Training in Addictions ResearchT32DA015035 · NIDA · WASHINGTON UNIVERSITY · PI Leopoldo J Cabassa, Patricia A Cavazos-Rehg · 2002 to 2026
$5.3M
Washington University Career Development Program in Drug Abuse and AddictionK12DA041449 · NIDA · WASHINGTON UNIVERSITY · PI Laura J. Bierut, Patricia A Cavazos-Rehg · 2017 to 2026
$4.2M
Medically-supervised withdrawal vs. agonist maintenance in the treatment of pregnant women with opioid use disorder: Maternal, fetal, and neonatal outcomesR01DA047867 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HEIL, SARAH H, JONES, HENDREE E · 2018 to 2022
$3.3M
Washington University Psychiatry Residency Research Education ProgramR25MH112473 · NIMH · WASHINGTON UNIVERSITY · PI NURI B FARBER, Timothy Eric Spiegel · 2018 to 2026
$1.6M
Adaptation and Refinement of a Clinically Applicable Phenotypic Battery to Individualize Opioid Use Disorder Treatment for Women Through the Postpartum PeriodK23DA053507 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI MARTIN, CAITLIN EILEEN · 2021 to 2025
$1.0M
Improving Treatment Engagement and Adherence to Optimize Outcomes for Opioid-Exposed Mother-Infant DyadsK23DA048169 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI SCHIFF, DAVIDA · 2019 to 2023
$998k
AN EXAMINATION OF AGE-RELATED DISPARITIES IN MEDICATION ASSISTED TREATMENT AND ASSOCIATED OUTCOMESR21DA044744 · NIDA · WASHINGTON UNIVERSITY · PI BIERUT, LAURA J. · 2017 to 2018
$419k
NCATS NIH HHS UL1 TR002345NIDA NIH HHS K12 DA041449NIDA NIH HHS K23 DA048169NIDA NIH HHS K23 DA053507NIDA NIH HHS R01 DA047867NIDA NIH HHS R21 DA044744NIDA NIH HHS T32 DA015035NIMH NIH HHS R25 MH112473NIMH NIH HHS R25 MH112473-01
6 · The paper itself

Abstract

backgroundAssociations between race/ethnicity and medications to treat OUD (MOUD), buprenorphine and methadone, in reproductive-age women have not been thoroughly studied in multi-state samples.

objectiveTo evaluate racial/ethnic variation in buprenorphine and methadone receipt and retention in a multi-state U.S. sample of Medicaid-enrolled, reproductive-age women with opioid use disorder (OUD) at the beginning of OUD treatment.

designRetrospective cohort study. SUBJECTS: Reproductive-age (18-45 years) women with OUD, in the Merative™ MarketScan® Multi-State Medicaid Database (2011-2016). MAIN MEASURES: Differences by race/ethnicity (non-Hispanic White, non-Hispanic Black, Hispanic, "other" race/ethnicity) in the likelihood of receiving buprenorphine and methadone during the start of OUD treatment (yes/no) were estimated using multivariable logistic regression. Differences in time to medication discontinuation (days) by race/ethnicity were evaluated using multivariable Cox regression.

resultsOf 66,550 reproductive-age Medicaid enrollees with OUD (84.1% non-Hispanic White, 5.9% non-Hispanic Black, 1.0% Hispanic, 5.3% "other"), 15,313 (23.0%) received buprenorphine and 6290 (9.5%) methadone. Non-Hispanic Black enrollees were less likely to receive buprenorphine (adjusted odds ratio, aOR = 0.76 [0.68-0.84]) and more likely to be referred to methadone clinics (aOR = 1.78 [1.60-2.00]) compared to non-Hispanic White participants. Across both buprenorphine and methadone in unadjusted analyses, the median discontinuation time for non-Hispanic Black enrollees was 123 days compared to 132 days and 141 days for non-Hispanic White and Hispanic enrollees respectively (χ

conclusionsOur data illustrate inequities between non-Hispanic Black and non-Hispanic White Medicaid enrollees with regard to buprenorphine and methadone utilization in the USA, consistent with literature on the racialized origins of methadone and buprenorphine treatment.

Indexed as

BuprenorphineOpioid-Related DisordersAdolescentAdultAnalgesics, OpioidFemaleHumansMedicaidMethadoneMiddle AgedOpiate Substitution TreatmentRetrospective StudiesUnited StatesYoung AdultAnalgesics, OpioidBuprenorphineMethadoneaddiction medicinebuprenorphinemethadoneopioid use disorderpregnancyracial disparities

Identifiers

PMID37436568
PMCPMC10713957
OpenAlexW4383998581

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.