ReviewNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2023
Pain assessment in autism: updating the ethical and methodological challenges through a state-of-the-art review.
Review in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.
- Long-term alterations in pain sensitivity following preterm birth: a systematic review and meta-analysis.Frontiers in pediatrics · 2026Pooled it
- Chronic Physical Pain in Children With and Without Autism Spectrum Disorder in the United States: Findings from the 2016 - 2021 National Survey of Children's Health.Journal of autism and developmental disorders · 2026Article
- A Reliable Effect of Alexithymia, but Not Autism, on Placebo Hypoalgesia.Autism : the international journal of research and practice · 2026Article
- Factors Associated With Postsurgical Pain in Children and Adolescents With Cognitive Dysfunction.Journal of clinical nursing · 2026Observational
- Individualized Therapeutic Environments for Pain Management in Children with Autism Spectrum Disorder: A Scoping Review.Children (Basel, Switzerland) · 2026Review
- Autistic women report high levels of pain, pain-related anxiety, and pain interference.Pain reports · 2025Article
- Taking an embodied avatar's perspective modulates the temporal dynamics of vicarious pain and pleasure: a virtual reality and EEG study.Social cognitive and affective neuroscience · 2025Article
- Pain perception in autism. A study of sensory reactivity in children and adolescents with autism using quantitative sensory testing and psychophysiological correlates.Frontiers in neuroscience · 2025Article
- Integrating tailored approaches in perioperative care strategies for neurodivergent individuals.EClinicalMedicine · 2024Review
- Interoception in Autism: A Narrative Review of Behavioral and Neurobiological Data.Psychology research and behavior management · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sensory features of autism include hypo- or hyper-reactivity to pain; however, previous studies on pain in autism lead to conflicting results. Here, we present the state of the art and the methodological challenges concerning pain perception in autism, focusing on studies that used standardized protocol as Quantitative Sensory Testing (QST) to measure perception. Despite there are still scant evidences found with the use of QST, they have challenged the presumed hyposensitivity to pain in autisms, which emerged from parents' reports. Both, peripheral and central mechanisms, have been found involved in typical features of perception in autism. Nonetheless, evidences with controlled protocols are still scarce, and even scarcer are studies focused on children. Overall, complex ethical challenges have to be overcome in order to collect subjective and objective measures from autistic children. With heterogeneous neurodevelopmental features, or intellectual disability, novel or modified protocols are needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.