Evidence map›Paper›PMID 37436190›Full record

ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2023

Comparison of different percutaneous revascularisation timing strategies in patients undergoing transcatheter aortic valve implantation.

Tobias Rheude, Giuliano Costa, Flavio Luciano Ribichini, Thomas Pilgrim, Ignacio J Amat Santos, Ole De Backer, Won-Keun Kim, Henrique Barbosa Ribeiro, Francesco Saia, Matjaz Bunc and 60 more

Abstract read
In one paragraph

Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Outcomes of complex, high-risk percutaneous coronary intervention in patients with severe aortic stenosis: the ASCoP registry.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Trial
  5. Article
  6. Observational
  7. Review
  8. Review
  9. Review
  10. Reply: Complex PCI in severe aortic stenosis: high risk, low reward?EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Article
  11. Review
  12. Article
  13. Coronary Artery Disease and Transcatheter Aortic Valve Replacement.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Review
  14. Article
  15. Review
  16. Article
  17. Transcatheter Aortic Valve Implantation Indications and Patient Selection.Interventional cardiology (London, England) · 2025
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

70 authors.

Tobias RheudeDepartment of Cardiovascular Diseases, German Heart Center Munich, Technical University Munich, Munich, Germany.
Giuliano CostaDivision of Cardiology, A.O.U. Policlinico "G. Rodolico-San Marco", Catania, Italy.
Flavio Luciano RibichiniDivision of Cardiology, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy.
Thomas PilgrimInselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Ignacio J Amat SantosCIBERCV, Division of Cardiology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
Ole De BackerThe Heart Center, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Won-Keun KimKerckhoff Heart Center, Bad Nauheim, Germany.
Henrique Barbosa RibeiroHeart Institute of Sao Paulo (InCor), University of Sao Paulo, Sao Paulo, Brazil.
Francesco SaiaCardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy and Cardiac Thoracic and Vascular Department, Università degli Studi di Bologna, Bologna, Italy.
Matjaz BuncUniversity Medical Centre Ljubljana, Ljubljana, Slovenia.
Didier TchétchéClinique Pasteur, Toulouse, France.
Philippe GarotInstitute Cardiovasculaire Paris Sud (ICPS), Hôpital Jacques Cartier, Ramsay Santé, Massy, France.
Darren MylotteGalway University Hospital, Galway, Ireland.
Francesco BurzottaFondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Yusuke WatanabeDepartment of Cardiology, Teikyo University School of Medicine, Tokyo, Japan.
Francesco BedogniDivision of Cardiology, IRCSS Policlinico San Donato, San Donato Milanese, Milano, Italy.
Tullio TesorioDivision of Cardiology, IRCSS Policlinico San Donato, San Donato Milanese, Milano, Italy.
Marco TocciDivision of Cardiology, Policlinico Umberto I, Roma, Italy.
Anna FranzoneDivision of Cardiology, AOU Federico II, Università di Napoli, Napoli, Italy.
Roberto ValvoUniversity of Catania, Catania, Italy.
Mikko SavontausHeart Center, Turku University Hospital, Turku, Finland.
Hendrik WienemannFaculty of Medicine and University Hospital Cologne, Clinic III for Internal Medicine, University of Cologne, Cologne, Germany.
Italo PortoCardiothoracic and Vascular Department, San Martino Policlinico Hospital, Genova, Italy.
Caterina GandolfoInterventional Cardiology Unit, IRCCS Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (ISMETT), Palermo, Italy.
Alessandro IadanzaUOSA Cardiologia Interventistica, Azienda ospedaliera-universitaria Senese, Policlinico Le Scotte, Siena, Italy.
Alessandro S BortoneDivision of University Cardiology, Cardiothoracic Department, Policlinico University Hospital, Bari, Italy.
Markus MachWien University Hospital, Vienna, Austria.
Azeem LatibMontefiore Medical Center, New York, NY, USA.
Luigi BiascoAzienda Sanitaria Locale di Ciriè, Chivasso e Ivrea, ASL TO4, Ivrea, Italy.
Maurizio TaramassoHerzZentrum Hirslanden Zürich, Zürich, Switzerland.
Marco ZimarinoDepartment of Cardiology, SS. Annunziata Hospital Chieti, ASL 2 Abruzzo, Chieti, Italy and Department of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy.
Daijiro TomiiInselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Philippe NuyensThe Heart Center, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Lars SondergaardAbbott Structural Heart, Santa Clara, CA, USA.
Sergio F CamaraHeart Institute of Sao Paulo (InCor), University of Sao Paulo, Sao Paulo, Brazil.
Tullio PalmeriniCardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy and Cardiac Thoracic and Vascular Department, Università degli Studi di Bologna, Bologna, Italy.
Mateusz OrzalkiewiczCardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy and Cardiac Thoracic and Vascular Department, Università degli Studi di Bologna, Bologna, Italy.
Klemen SteblovnikUniversity Medical Centre Ljubljana, Ljubljana, Slovenia.
Bastien DegrelleClinique Pasteur, Toulouse, France.
Alexandre GautierInstitute Cardiovasculaire Paris Sud (ICPS), Hôpital Jacques Cartier, Ramsay Santé, Massy, France.
Paolo Alberto Del SoleDivision of Cardiology, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy.
Andrea MainardiDivision of Cardiology, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy.
Michele PighiDivision of Cardiology, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy.
Mattia LunardiDivision of Cardiology, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy.
Hideyuki KawashimaDepartment of Cardiology, Teikyo University School of Medicine, Tokyo, Japan.
Enrico CriscioneDivision of Cardiology, IRCSS Policlinico San Donato, San Donato Milanese, Milano, Italy.
Vincenzo CesarioSant'Andrea Hospital, Sapienza University, Rome, Italy.
Fausto BiancariClinica Montevergine, GVM Care & Research, Mercogliano, Italy.
Federico ZaninClinica Montevergine, GVM Care & Research, Mercogliano, Italy.
Giovanni EspositoDivision of Cardiology, AOU Federico II, Università di Napoli, Napoli, Italy.
Matti AdamFaculty of Medicine and University Hospital Cologne, Clinic III for Internal Medicine, University of Cologne, Cologne, Germany.
Eberhard GrubeFaculty of Medicine and University Hospital Cologne, Clinic III for Internal Medicine, University of Cologne, Cologne, Germany.
Stephan BaldusFaculty of Medicine and University Hospital Cologne, Clinic III for Internal Medicine, University of Cologne, Cologne, Germany.
Vincenzo De MarzoCardiothoracic and Vascular Department, San Martino Policlinico Hospital, Genova, Italy.
Elisa PireddaCardiothoracic and Vascular Department, San Martino Policlinico Hospital, Genova, Italy.
Stefano CannataInterventional Cardiology Unit, IRCCS Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (ISMETT), Palermo, Italy.
Fortunato IacovelliDivision of University Cardiology, Cardiothoracic Department, Policlinico University Hospital, Bari, Italy.
Martin AndreasWien University Hospital, Vienna, Austria.
Valentina FrittittaUniversity of Catania, Catania, Italy.
Elena DipietroUniversity of Catania, Catania, Italy.
Claudia ReddavidUniversity of Catania, Catania, Italy.
Orazio StrazzieriUniversity of Catania, Catania, Italy.
Silvia MottaUniversity of Catania, Catania, Italy.
Domenico AngellottiDivision of Cardiology, AOU Federico II, Università di Napoli, Napoli, Italy.
Carmelo SgroiDivision of Cardiology, A.O.U. Policlinico "G. Rodolico-San Marco", Catania, Italy.
Erion XhepaDepartment of Cardiovascular Diseases, German Heart Center Munich, Technical University Munich, Munich, Germany.
Faraj KargoliMontefiore Medical Center, New York, NY, USA.
Corrado TamburinoDivision of Cardiology, A.O.U. Policlinico "G. Rodolico-San Marco", Catania, Italy.
Michael JonerDepartment of Cardiovascular Diseases, German Heart Center Munich, Technical University Munich, Munich, Germany.
Marco BarbantiDivision of Cardiology, A.O.U. Policlinico "G. Rodolico-San Marco", Catania, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe optimal timing to perform percutaneous coronary interventions (PCI) in transcatheter aortic valve implantation (TAVI) patients remains unknown.

aimsWe sought to compare different PCI timing strategies in TAVI patients.

methodsThe REVASC-TAVI registry is an international registry including patients undergoing TAVI with significant, stable coronary artery disease (CAD) at preprocedural workup. In this analysis, patients scheduled to undergo PCI before, after or concomitantly with TAVI were included. The main endpoints were all-cause death and a composite of all-cause death, stroke, myocardial infarction (MI) or rehospitalisation for congestive heart failure (CHF) at 2 years. Outcomes were adjusted using the inverse probability treatment weighting (IPTW) method.

resultsA total of 1,603 patients were included. PCI was performed before, after or concomitantly with TAVI in 65.6% (n=1,052), 9.8% (n=157) or 24.6% (n=394), respectively. At 2 years, all-cause death was significantly lower in patients undergoing PCI after TAVI as compared with PCI before or concomitantly with TAVI (6.8% vs 20.1% vs 20.6%; p<0.001). Likewise, the composite endpoint was significantly lower in patients undergoing PCI after TAVI as compared with PCI before or concomitantly with TAVI (17.4% vs 30.4% vs 30.0%; p=0.003). Results were confirmed at landmark analyses considering events from 0 to 30 days and from 31 to 720 days.

conclusionsIn patients with severe aortic stenosis and stable coronary artery disease scheduled for TAVI, performance of PCI after TAVI seems to be associated with improved 2-year clinical outcomes compared with other revascularisation timing strategies. These results need to be confirmed in randomised clinical trials.

Indexed as

Aortic Valve StenosisCoronary Artery DiseaseMyocardial InfarctionPercutaneous Coronary InterventionTranscatheter Aortic Valve ReplacementAortic ValveHumansRisk FactorsTreatment Outcome

Identifiers

PMID37436190
PMCPMC10495747

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