ArticleJournal of the American Chemical Society2023
Ru-NHC-Catalyzed Asymmetric, Complete Hydrogenation of Indoles and Benzofurans: One Catalyst with Dual Function.
Article in Journal of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Enantioselective Rh-catalyzed addition of indoles to enones and the key role of the free N-H group with acyclic enones.Chemical science · 2026Article
- Chiral Spiro-Scaffolded C(spAngewandte Chemie (International ed. in English) · 2026Article
- N-Heterocyclic carbenes on copper: a dynamic and sensitive interplay between surface functionalization and etching.Chemical science · 2026Article
- Atroposelective Dearomative Cross-Coupling of Benzofuran Derivatives by Z-Selective Functionalization of the Vinyl C─O Bond.Angewandte Chemie (International ed. in English) · 2026Article
- Transition-Metal-Based Dearomatization Strategy for the Synthesis of FunctionalizedOrganometallics · 2025Article
- Synthesis of Chiral δ-Aminoboronic Esters by Enantioselective Hydrogenation of 1,2-Azaborines.Angewandte Chemie (International ed. in English) · 2025Article
- Access to C(spRSC advances · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The highly enantioselective and complete hydrogenation of protected indoles and benzofurans has been developed, affording facile access to a range of chiral three-dimensional octahydroindoles and octahydrobenzofurans, which are prevalent in many bioactive molecules and organocatalysts. Remarkably, we are in control of the nature of the ruthenium N-heterocyclic carbene complex and employed the complex as both homogeneous and heterogeneous catalysts, providing new avenues for its potential applications in the asymmetric hydrogenation of more challenging aromatic compounds.
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Registered trials
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