ArticleDevelopment (Cambridge, England)2023
DELLA proteins positively regulate seed size in Arabidopsis.
Article in Development (Cambridge, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- Molecular mechanisms underlying seed enlargement mediated by seed coat development in autotetraploid castor bean.The Plant journal : for cell and molecular biology · 2026Article
- Review
- Membrane-associated DELLA degradation modulates growth under carbon/nitrogen imbalance.The Plant cell · 2026Article
- Article
- Article
- Identification and Candidate Gene Analysis ofInternational journal of molecular sciences · 2025Article
- New insights intoFrontiers in plant science · 2025Article
- Hormonal regulation and crosstalk during early endosperm and seed coat development.Plant reproduction · 2024Review
- When Size Matters: New Insights on How Seed Size Can Contribute to the Early Stages of Plant Development.Plants (Basel, Switzerland) · 2024Review
- Unveiling the imprinted dance: how parental genomes orchestrate seed development and hybrid success.Frontiers in plant science · 2024Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human and animal nutrition is mainly based on seeds. Seed size is a key factor affecting seed yield and has thus been one of the primary objectives of plant breeders since the domestication of crop plants. Seed size is coordinately regulated by signals of maternal and zygotic tissues that control the growth of the seed coat, endosperm and embryo. Here, we provide previously unreported evidence for the role of DELLA proteins, key repressors of gibberellin responses, in the maternal control of seed size. The gain-of-function della mutant gai-1 produces larger seeds as a result of an increase in the cell number in ovule integuments. This leads to an increase in ovule size and, in turn, to an increase in seed size. Moreover, DELLA activity promotes increased seed size by inducing the transcriptional activation of AINTEGUMENTA, a genetic factor that controls cell proliferation and organ growth, in the ovule integuments of gai-1. Overall, our results indicate that DELLA proteins are involved in the control of seed size and suggest that modulation of the DELLA-dependent pathway could be used to improve crop yield.
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Registered trials
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