Evidence map›Paper›PMID 37435630›Full record

ReviewJournal of clinical laboratory analysis2023

The impact and role of identified long noncoding RNAs in nonalcoholic fatty liver disease: A narrative review.

Na Shi, Kang Sun, Haiying Tang, Jingwei Mao

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical laboratory analysis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Long Noncoding RNAs in Diet-Induced Metabolic Diseases.International journal of molecular sciences · 2024
    Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Na ShiDepartment of Gastroenterology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Kang SunDepartment of Gastroenterology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Haiying TangDepartment of Respiratory and Critical Care Medicine, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Jingwei MaoDepartment of Gastroenterology, First Affiliated Hospital of Dalian Medical University, Dalian, China.ORCID https://orcid.org/0000-0003-1896-1988
Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide, but its mechanism and pathophysiology remain unclear. Long noncoding RNAs (lncRNAs) may exert a vital influence on regulating various biological functions in NAFLD.

methodsThe databases such as Google Scholar, PubMed, and Medline were searched using the following keywords: nonalcoholic fatty liver disease, nonalcoholic fatty liver disease, NAFLD, nonalcoholic steatohepatitis, nonalcoholic steatohepatitis, NASH, long noncoding RNAs, and lncRNAs. Considering the titles and abstracts, unrelated studies were excluded. The authors evaluated the full texts of the remaining studies.

resultsWe summarized the current knowledge of lncRNAs and the main signaling pathways of lncRNAs involved in NAFLD explored in recent years. As a heterogeneous group of noncoding RNAs (ncRNAs), lncRNAs play crucial roles in biological processes underlying the pathophysiology of NAFLD. The mechanisms, particularly those associated with the regulation of the expression and activities of lncRNAs, play important roles in NAFLD.

conclusionA better comprehension of the mechanism controlled by lncRNAs in NAFLD is necessary for the identification of novel therapeutic targets for drug development and improved, noninvasive methods for diagnosis.

Indexed as

Non-alcoholic Fatty Liver DiseaseRNA, Long NoncodingHumansLiverRNA, Long Noncodinghepatocyteslong noncoding RNAnonalcoholic fatty liver diseasenonalcoholic steatohepatitissignaling pathway

Identifiers

PMID37435630
PMCPMC10431402
OpenAlexW4383998765

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.