Evidence map›Paper›PMID 37435596›Full record

ArticleFrontiers in sports and active living2023

Myocarditis and sports in the young: data from a nationwide registry on myocarditis-"MYKKE-Sport".

Isabelle Schöffl, Sophia Holler, Sven Dittrich, Thomas Pickardt, Bernd Opgen-Rhein, Martin Boehne, Bardo Wannenmacher, Katja Reineke, Gesa Wiegand, Tobias Hecht and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in sports and active living, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 11 institutions in 2 countries.

Isabelle SchöfflDepartment of Pediatric Cardiology, Friedrich-Alexander-Universität, Erlangen-Nürnberg, Germany.
Sophia HollerDepartment of Pediatric Cardiology, Friedrich-Alexander-Universität, Erlangen-Nürnberg, Germany.
Sven DittrichDepartment of Pediatric Cardiology, Friedrich-Alexander-Universität, Erlangen-Nürnberg, Germany.
Thomas PickardtCompetence Network for Congenital Heart Defects, Berlin, Germany.
Bernd Opgen-RheinDepartment of Pediatric Cardiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Martin BoehneDepartment of Paediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.
Bardo WannenmacherClinic for Paediatric Cardiology, Heart Centre, University of Leipzig, Leipzig, Germany.
Katja ReinekeDepartment for Paediatric Cardiology, University Heart Center Freiburg, Freiburg, Germany.
Gesa WiegandDepartment for Paediatric Cardiology, University Hospital Tübingen, Tübingen, Germany.
Tobias HechtHeart- and Diabetes Center North Rhine-Westphalia, Center of Pediatric Cardiology and Congenital Heart Disease, Ruhr University Bochum, Bad Oeynhausen, Germany.
Michael KaestnerPediatric Cardiology, University Hospital Ulm, Ulm, Germany.
Daniel MessroghliDepartment of Cardiology, German Heart Center Berlin, Berlin, Germany.
Stephan SchubertHeart- and Diabetes Center North Rhine-Westphalia, Center of Pediatric Cardiology and Congenital Heart Disease, Ruhr University Bochum, Bad Oeynhausen, Germany.
Franziska SeidelDepartment of Pediatric Cardiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Annika WeigeltDepartment of Pediatric Cardiology, Friedrich-Alexander-Universität, Erlangen-Nürnberg, Germany.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEDeutsches Herzzentrum der Charité · DEDeutsches Herzzentrum München · DECharité - Universitätsmedizin Berlin · DEHeart and Diabetes Center North Rhine-Westphalia · DELeeds Beckett University · GBLeipzig Heart Institute · DEMedizinische Hochschule Hannover · DEUniversitäts-Herzzentrum Freiburg-Bad Krozingen · DEUniversity Children's Hospital Tübingen · DEUniversity Hospital Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Myocarditis represents one of the most common causes of Sudden Cardiac Death in children. Myocardial involvement during a viral infection is believed to be higher as a consequence of intensive exertion. Recommendations for return to sports are based on cohort and case studies only. This study aims to investigate the relationship between physical activity and myocarditis in the young. Patient: Every patient in the MYKKE registry fulfilling criteria for suspicion of myocarditis was sent a questionnaire regarding the physical activity before, during and after the onset of myocarditis. Method: This study is a subproject within the MYKKE registry, a multicenter registry for children and adolescents with suspected myocarditis. The observation period for this analysis was 93 months (September 2013-June 2021). Anamnestic, cardiac magnetic resonance images, echocardiography, biopsy and laboratory records from every patient were retrieved from the MYKKE registry database. Results: 58 patients (mean age 14.6 years) were enrolled from 10 centers. Most patients participated in curricular physical activity and 36% in competitive sports before the onset of myocarditis. There was no significant difference of heart function at admission between the physically active and inactive subjects (ejection fraction of 51.8 ± 8.6% for the active group vs. 54.4 ± 7.7% for the inactive group). The recommendations regarding the return to sports varied widely and followed current guidelines in 45%. Most patients did not receive an exercise test before returning to sports. Conclusion: Sports before the onset of myocarditis was not associated with a more severe outcome. There is still a discrepancy between current literature and actual recommendations given by health care providers. The fact that most participants did not receive an exercise test before being cleared for sports represents a serious omission.

Indexed as

cardiomyopathyheart muscle infectionpreventionreturn to sportssudden cardiac death

Identifiers

PMID37435596
PMCPMC10331598
OpenAlexW4382023484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.