Evidence map›Paper›PMID 37435485›Full record

ArticleFrontiers in endocrinology2023

Mutation of brain aromatase disrupts spawning behavior and reproductive health in female zebrafish.

Katherine Shaw, Mylène Therrien, Chunyu Lu, Xiaochun Liu, Vance L Trudeau

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Editorial: Steroids and the brain, volume II.Frontiers in endocrinology · 2025
    Article
  4. Cyp19a1a Promotes Ovarian Maturation through Regulating E2 Synthesis withInternational journal of molecular sciences · 2024
    Article
  5. Article
  6. Control of social status by sex steroids: insights from teleost fishes.Molecular psychology : brain, behavior, and society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Katherine ShawDepartment of Biology, University of Ottawa, Ottawa, ON, Canada.
Mylène TherrienDepartment of Biology, University of Ottawa, Ottawa, ON, Canada.
Chunyu LuDepartment of Biology, University of Ottawa, Ottawa, ON, Canada.
Xiaochun LiuState Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Province Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.
Vance L TrudeauDepartment of Biology, University of Ottawa, Ottawa, ON, Canada.
University of Ottawa · CASun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aromatase (Cyp19a1) is the steroidogenic enzyme that converts androgens into bioactive estrogens, and hence is in a pivotal position to mediate reproduction and sexual behavior. In teleosts, there are two aromatase paralogs:

Indexed as

AromataseSexual Behavior, AnimalZebrafishZebrafish ProteinsAndrogensAnimalsBrainFemaleMaleReproductionAndrogensAromataseCyp19a1a protein, zebrafishZebrafish Proteinsaromatasebraincyp19a1bestrogenhormoneneuroendocrinesexual behaviorzebrafish

Identifiers

PMID37435485
PMCPMC10332311
OpenAlexW4382139447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.