Evidence map›Paper›PMID 37435356›Full record

ArticleNeurotrauma reports2023

Mature and Myelinating Oligodendrocytes Are Specifically Vulnerable to Mild Fluid Percussion Injury in Mice.

Alexandra A Adams, Teresa L Wood, Haesun A Kim

Open access · goldAbstract read
In one paragraph

Article in Neurotrauma reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alexandra A AdamsDepartment of Biological Sciences, Physiology, and Neuroscience, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA.
Teresa L WoodDepartment of Pharmacology, Physiology, and Neuroscience, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA.
Haesun A KimDepartment of Biological Sciences, Physiology, and Neuroscience, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA.
Rutgers, The State University of New Jersey · US

Funding

RO1NS118020 Research Supplements to Promote Diversity in Health-Related ResearchR01NS118020 · NINDS · RUTGERS THE STATE UNIV OF NJ NEWARK · PI KIM, HAESUN A · 2020 to 2024
$1.9M
Impact of mechanical injury on oligodendrocyte myelin homeostasis in adult brainR21NS109708 · NINDS · RUTGERS THE STATE UNIV OF NJ NEWARK · PI KIM, HAESUN A · 2018 to 2019
$426k
NINDS NIH HHS R01 NS118020NINDS NIH HHS R21 NS109708
6 · The paper itself

Abstract

Myelin loss and oligodendrocyte death are well documented in patients with traumatic brain injury (TBI), as well as in experimental animal models after moderate-to-severe TBI. In comparison, mild TBI (mTBI) does not necessarily result in myelin loss or oligodendrocyte death, but causes structural alterations in the myelin. To gain more insight into the impact of mTBI on oligodendrocyte lineage in the adult brain, we subjected mice to mild lateral fluid percussion injury (mFPI) and characterized the early impact (1 and 3 days post-injury) on oligodendrocytes in the corpus callosum using multiple oligodendrocyte lineage markers (platelet-derived growth factor receptor [PDGFR]-α, glutathione

Indexed as

BCAS1CC1corpus callosumFluoroMyelin™GST-πmild TBIoligodendrocytes

Identifiers

PMID37435356
PMCPMC10331160
OpenAlexW4382602323

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.