Evidence map›Paper›PMID 37435235›Full record

ArticleInfection and drug resistance2023

Cryptococcosis in Southern China: Insights from a Six-Year Retrospective Study in Eastern Guangdong.

Hazrat Bilal, Dongxing Zhang, Muhammad Shafiq, Muhammad Nadeem Khan, Canhua Chen, Sabir Khan, Qian Wang, Lin Cai, Muhammad Awais, Haibin Hu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Hazrat BilalDepartment of Dermatology, Second Affiliated Hospital of Shantou University Medical College, Shantou, 515041, People's Republic of China.
Dongxing ZhangDepartment of Dermatology, Meizhou Dongshan Hospital, Meizhou, Guangdong Province, 514023, People's Republic of China.
Muhammad ShafiqDepartment of Cell Biology and Genetics, Shantou University Medical College, Shantou, People's Republic of China.ORCID 0000-0002-4346-5903
Muhammad Nadeem KhanFaculty of Biological Sciences, Department of Microbiology, Quaid-I-Azam University, Islamabad, 45320, Pakistan.
Canhua ChenClinical Laboratory, Meizhou People's Hospital, Meizhou, Guangdong Province, 514023, People's Republic of China.
Sabir KhanDepartment of Dermatology, Second Affiliated Hospital of Shantou University Medical College, Shantou, 515041, People's Republic of China.
Qian WangDepartment of Dermatology, Second Affiliated Hospital of Shantou University Medical College, Shantou, 515041, People's Republic of China.ORCID 0009-0009-2915-2925
Lin CaiDepartment of Dermatology, Second Affiliated Hospital of Shantou University Medical College, Shantou, 515041, People's Republic of China.
Muhammad AwaisDepartment of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming, Yunnan, People's Republic of China.
Haibin HuThe First Clinical Medical college, Guangdong Medical University, Zhanjiang, 523808, People's Republic of China.
Yuebin ZengDepartment of Dermatology, Second Affiliated Hospital of Shantou University Medical College, Shantou, 515041, People's Republic of China.ORCID 0000-0003-0850-7562
Shantou University · CNMeizhou City People's Hospital · CNGuangdong Medical College · CNKunming University of Science and Technology · CNQuaid-i-Azam University · PKSichuan University · CNUniversity of Sassari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Cryptococcosis is a fatal infection that can affect both immunocompetent and immunocompromised patients, and it is little understood in China's various regions. This research aimed to look at the epidemiology, risk factors, and antifungal susceptibility pattern of Methods: A six-year (2016-2022) retrospective study was conducted at Meizhou People's Hospital, China. Demographical, clinical, and laboratory data of cryptococcal patients were collected from hospital records and statistically analyzed using the chi-square and ANOVA tests. Results: Overall, 170 cryptococcal infections were recorded, of which meningitis accounted for 78 (45.88%), cryptococcemia for 50 (29.41%), and pneumonia for 42 (24.7%). The number of cases increased 8-fold during the study duration. The median age of patients was 58 years (Inter quartile range: 47-66), and the high proportion of cases was from the male population (n = 121, 71.17%). The underlying diseases were identified only in 60 (35.29%) patients, of which 26 (15.29%) were severely immunocompromised, and 26 (15.29%) others were mildly immunocompromised. A statistically significant difference was reported for chronic renal failure, and anemia ( Conclusion: In high-risk populations, cryptococcal infections require ongoing monitoring and management.

Indexed as

antifungal susceptibilitycryptococcosisCryptococcus neoformansepidemiologyrisk factors

Identifiers

PMID37435235
PMCPMC10332366
OpenAlexW4383344047

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.