ArticleSAGE open medical case reports2023
Ectopic parathyroid adenoma causing hyperparathyroidism-induced psychosis: A case report.
Article in SAGE open medical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Constipation as an Atypical Presentation of Hyperparathyroidism: A Case Report.The American journal of case reports · 2025Article
- Middle-aged man with primary hyperparathyroidism-associated psychosis: A case report.PCN reports : psychiatry and clinical neurosciences · 2025Article
- An Analysis of Primary Hyperparathyroidism in Association with Depression or Anxiety.Diseases (Basel, Switzerland) · 2025Review
- Atypically presented dysphagia in a patient with primary hyperparathyroidism that resolved after parathyroidectomy: A case report.International journal of surgery case reports · 2024Article
- Hyperparathroidism-induced acute psychosis.Industrial psychiatry journal · 2024Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary hyperparathyroidism is a disease with multisystemic and heterogeneous manifestations, characterized by underlying high parathormone concentrations. Despite neuropsychiatric involvement being one of the manifestations, psychosis is rare. This is the case of a 68-year-old female with a 10-day clinical course of anorexia, mutism, dysphagia, constipation, and weight loss. The patient had disorganized speech associated with paranoid delusions. Prior to this visit, the patient was recently diagnosed with a mixed anxiety-depressive disorder. For this reason, treatment with antidepressants in combination with atypical antipsychotics was administered without a satisfactory response. Neuroimaging, infectious panel, and toxicology screening showed no abnormal findings. Hypercalcemia secondary to a retropharyngeal ectopic parathyroid adenoma was the causative etiology of her primary hyperparathyroidism, and hypercalcemia treatment resolved the psychotic episode. We highlight the importance of recognizing psychosis as a possible initial presentation of hyperparathyroidism and hypercalcemia. Ruling out organic etiologies prior to diagnosing a primary cause of psychosis is crucial, as their treatment can reverse the psychotic symptoms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.