ArticleAmerican journal of translational research2023
A combined index constructed based on NLR and PLR is associated with in-hospital mortality risk in patients with acute myocardial infarction.
Article in American journal of translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Article
- Exploring the Link Between Inflammatory Biomarkers (SII, SIRI, PLR, NLR, LMR) and Migraine in Young and Early Middle-Aged US Adults: Evidence From NHANES 1999-2004 and Machine Learning Models.Brain and behavior · 2025Article
- Development and Validation of a Nomogram to Predict Ventricular Fibrillation During Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction.Reviews in cardiovascular medicine · 2025Article
- Prognostic value of nine inflammatory biomarkers for critically ill patients with rheumatic heart disease: a retrospective study.Frontiers in immunology · 2025Article
- Prognostic value of inflammatory markers for all-cause mortality in patients with acute myocardial infarction in the coronary care unit: a retrospective study based on MIMIC-IV database.Frontiers in cardiovascular medicine · 2025Article
- Relationship between inflammatory markers and long-term prognosis in ICU patients with acute non-ST-segment elevation myocardial infarction.Frontiers in cardiovascular medicine · 2025Article
- The Prognostic Role of the Neutrophil-to-Lymphocytes Ratio in the Most Frequent Cardiovascular Diseases: An Update.Life (Basel, Switzerland) · 2024Review
- Diagnostic value of the creatine kinase-MB/creatine kinase and neutrophil/lymphocyte ratios in acute myocardial infarction.Journal of cardiothoracic surgery · 2024Article
- The Prognostic Role of Platelet-to-Lymphocyte Ratio in Acute Coronary Syndromes: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2023Review
- Assessment of Inflammatory Hematological Ratios (NLR, PLR, MLR, LMR and Monocyte/HDL-Cholesterol Ratio) in Acute Myocardial Infarction and Particularities in Young Patients.International journal of molecular sciences · 2023Review
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Authors and funding
6 authors.
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Abstract
objectiveTo explore the validity of the neutrophil-to-lymphocyte ratio (NLR) combined with the platelet-to-lymphocyte ratio (PLR) in predicting the short-term prognosis of acute myocardial infarction (AMI).
methodsWe collected the data from a total of 3,246 clinical AMI patients hospitalized in the Second Affiliated Hospital of Dalian Medical University from December 2015 to December 2021. All patients underwent routine blood examination within 2 hours of admission. Outcome was defined as all-cause mortality during hospitalization. A total of 94 pairs of patients were generated by propensity score matching (PSM), and a combined NLR-based and PLR-based indicators was constructed according to receiver operating characteristic (ROC) curves and multivariate logistic regression analysis.
resultsWe finally generated 94 pairs of patients by PSM, and analyzed NLR and PLR in those patients using ROC curves, and converted NLR (optimal cut-off = 5.094) and PLR (optimal cut-off = 165.413) into binary variables according to optimal cut-offs, defined as NLR grouping (5.094 vs. > 5.094, ≤ 5.094 = 0, > 5.094 = 1) and PLR grouping (165.413 vs. > 165.413, ≤ 165.413 = 0, > 165.413 = 1). We constructed a combined indicator (NLR grouping + PLR grouping) based on the results of multivariate logistic regression. Combined indicator has four conditions [Y
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