Evidence map›Paper›PMID 37434704›Full record

ArticleFrontiers in microbiology2023

16S rRNA gene sequencing reveals the correlation between the gut microbiota and the susceptibility to pathological scars.

Ming Li, Minghao Li, Yingting Dai, Dang Li, Han Yu, Jian Liu, Hangqi Gao, Yi Zhong, Mingquan Huang, Jing Lin and 3 more

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ming Li *Department of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.
Minghao Li *Department of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.
Yingting Dai *Department of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.
Dang LiNursing Department of Fujian Medical University Union Hospital, Fuzhou, China.
Han YuDepartment of Dermatology, Pingtan Comprehensive Experimental Area Hospital, Fuzhou, China.
Jian LiuFuzhou MineButy Clinics, Fuzhou, China.
Hangqi GaoDepartment of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.
Yi ZhongDepartment of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.
Mingquan HuangDepartment of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.
Jing LinDepartment of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.
Yide XieDepartment of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.
Zhihui GuoDepartment of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.
Xiaosong ChenDepartment of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiome profile in patients with pathological scars remains rarely known, especially those patients who are susceptible to pathological scars. Previous studies demonstrated that gut microbial dysbiosis can promote the development of a series of diseases via the interaction between gut microbiota and host. The current study aimed to explore the gut microbiota of patients who are prone to suffer from pathological scars. 35 patients with pathological scars (PS group) and 40 patients with normal scars (NS group) were recruited for collection of fecal samples to sequence the 16S ribosomal RNA (16S rRNA) V3-V4 region of gut microbiota. Alpha diversity of gut microbiota showed a significant difference between NS group and PS group, and beta diversity indicated that the composition of gut microbiota in NS and PS participants was different, which implied that dysbiosis exhibits in patients who are susceptible to pathological scars. Based on phylum, genus, species levels, we demonstrated that the changing in some gut microbiota (

Indexed as

16S rRNA sequencingdysbiosisgut microbiotapathological scarssusceptibility

Identifiers

PMID37434704
PMCPMC10332274

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.