Evidence map›Paper›PMID 37434581›Full record

ArticleNMR in biomedicine2023

Time-dependent diffusion tensor imaging and diffusion modeling of age-related differences in the medial gastrocnemius and feasibility study of correlations to histopathology.

Vadim Malis, Usha Sinha, Edward Smitaman, Jed Keenan Lim Obra, Henning T Langer, Agata A Mossakowski, Keith Baar, Shantanu Sinha

Open access · greenAbstract read
In one paragraph

Article in NMR in biomedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Magnetic Resonance Imaging Biomarkers of Muscle.Tomography (Ann Arbor, Mich.) · 2024
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Vadim MalisPhysics, UC San Diego, San Diego, California, USA.ORCID 0000-0002-0426-1457
Usha SinhaPhysics, San Diego State University, San Diego, California, USA.
Edward SmitamanDepartment of Radiology, UC San Diego, San Diego, California, USA.
Jed Keenan Lim ObraDepartment of Physiology and Membrane Biology, UC Davis, Davis, California, USA.
Henning T LangerDepartment of Physiology and Membrane Biology, UC Davis, Davis, California, USA.
Agata A MossakowskiDepartment of Physiology and Membrane Biology, UC Davis, Davis, California, USA.
Keith BaarDepartment of Physiology and Membrane Biology, UC Davis, Davis, California, USA.
Shantanu SinhaMuscle Imaging and Modeling Lab, Department of Radiology, UC San Diego, San Diego, California, USA.
UC San Diego Health System · USUniversity of California, Davis · USHumboldt-Universität zu Berlin · DESan Diego State University · US

Funding

Role of the Extracellular Matrix in Age-Associated Strength Loss: Combining Imaging and Biochemistry to create a Multi-Scale Mesh-free ModelR01AG056999 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SINHA, SHANTANU · 2018 to 2022
$3.1M
NIA NIH HHS R01 AG056999NIH HHS 5R01AG056999
6 · The paper itself

Abstract

purposeImplement STEAM-DTI to model time-dependent diffusion eigenvalues using the random permeable barrier model (RPBM) to study age-related differences in the medial gastrocnemius (MG) muscle. Validate diffusion model-extracted fiber diameter for histological assessment.

methodsDiffusion imaging at different diffusion times (Δ) was performed on seven young and six senior participants. Time-dependent diffusion eigenvalues (λ

resultsλ

conclusionThe age-related patterns in λ

Indexed as

AgingDiffusion Tensor ImagingFeasibility StudiesMuscle, SkeletalAdultAgedAged, 80 and overDiffusionFemaleHumansMaleMiddle AgedModels, BiologicalTime FactorsYoung Adultaging muscleimaging-biopsy correlationimaging-physical assessment correlationrandom permeable barrier modelingSTEAM-DTI

Identifiers

PMID37434581
PMCPMC10592510
OpenAlexW4383998600

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.