Evidence map›Paper›PMID 37434152›Full record

ArticleBMC genomics2023

Whole-genome resequencing of the native sheep provides insights into the microevolution and identifies genes associated with reproduction traits.

Mengting Zhu, Yonglin Yang, Hua Yang, Zongsheng Zhao, Hongmei Zhang, Hugh T Blair, Wei Zheng, Mingyuan Wang, Chenhui Fang, Qian Yu and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
14.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Mengting Zhu *State Key Laboratory of Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Science, Shihezi, China.
Yonglin Yang *State Key Laboratory of Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Science, Shihezi, China.
Hua YangState Key Laboratory of Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Science, Shihezi, China. yhxjcn@sina.com.
Zongsheng ZhaoCollege of Animal Science and Technology, Shihezi University, Shihezi, Xinjiang, China. zhaozongsh@shzu.edu.cn.
Hongmei ZhangFirst Affiliated Hospital, School of Medical College, Shihezi University, Shihezi, Xinjiang, China.
Hugh T BlairInstitute Veterinary, Animal & Biomedical Sciences, Massey University, Auckland, Palmerston North, New Zealand.
Wei ZhengCollege of Animal Science and Technology, Shihezi University, Shihezi, Xinjiang, China.
Mingyuan WangState Key Laboratory of Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Science, Shihezi, China.
Chenhui FangCollege of Animal Science and Technology, Shihezi University, Shihezi, Xinjiang, China.
Qian YuState Key Laboratory of Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Science, Shihezi, China.
Huaqian ZhouCollege of Animal Science and Technology, Shihezi University, Shihezi, Xinjiang, China.
Hangdong QiCollege of Animal Science and Technology, Shihezi University, Shihezi, Xinjiang, China.
Shihezi University · CNXinjiang Academy of Agricultural and Reclamation Science · CNFirst Affiliated Hospital of Shihezi University Medical College · CNMassey University · NZ

Funding

Agricultural Science and Technology Innovation Project of the Xinjiang Production and Construction Corps NCG202211Major Scientific and Technological Project of the Xinjiang Production and Construction Corps 2017AA006National Key R&D Program of China 2021YFD1300903-2National Natural Science Foundation of China 32160770the Open Project of State Key Laboratory of Sheep Genetic Improvement and Healthy Production MYSKLKF201902
6 · The paper itself

Abstract

backgroundSheep genomes undergo numerous genes losses, gains and mutation that generates genome variability among breeds of the same species after long time natural and artificial selection. However, the microevolution of native sheep in northwest China remains elusive. Our aim was to compare the genomes and relevant reproductive traits of four sheep breeds from different climatic environments, to unveil the selection challenges that this species cope with, and the microevolutionary differences in sheep genomes. Here, we resequenced the genomes of 4 representative sheep breeds in northwest China, including Kazakh sheep and Duolang sheep of native breeds, and Hu sheep and Suffolk sheep of exotic breeds with different reproductive characteristics.

resultsWe found that these four breeds had a similar expansion experience from ~ 10,000 to 1,000,000 years ago. In the past 10,000 years, the selection intensity of the four breeds was inconsistent, resulting in differences in reproductive traits. We explored the sheep variome and selection signatures by F

conclusionsOur results provide insights into the microevolution of native sheep and valuable genomic information for identifying genes associated with important reproductive traits in sheep.

Indexed as

Cytochrome P-450 CYP1A1GenomicsAnimalsChinaReproductionSequence Analysis, DNASheepCytochrome P-450 CYP1A1GWASMicroevolutionReproductive traitSelection signatureSheepWhole-genome resequencing

Identifiers

PMID37434152
PMCPMC10334551
OpenAlexW4383908703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.