Evidence map›Paper›PMID 37433991›Full record

ArticleJournal of clinical immunology2023

Chronic Granulomatous Disease: a Cohort of 173 Patients-10-Years Single Center Experience from Egypt.

Dalia Abd Elaziz, Rabab El Hawary, Safa Meshaal, Radwa Alkady, Sohilla Lotfy, Alia Eldash, Aya Erfan, Engy Chohayeb, Mai Saad, Jeannette Boutros and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 11 citations in OpenAlex.

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  12. [Chest computed tomography manifestations in neonates with chronic granulomatous disease].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Dalia Abd ElazizPediatric Department, Faculty of Medicine, Cairo University, Cairo, Egypt. dalia.abdelaziz@kasralainy.edu.eg.ORCID http://orcid.org/0000-0002-7830-7008
Rabab El HawaryClinical Pathology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Safa MeshaalClinical Pathology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Radwa AlkadyPediatric Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Sohilla LotfyPediatric Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Alia EldashClinical Pathology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Aya ErfanClinical Pathology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Engy ChohayebPediatric Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Mai SaadPediatric Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Jeannette BoutrosPediatric Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Nermeen GalalPediatric Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Aisha ElmarsafyPediatric Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Cairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeChronic granulomatous disease (CGD) is an inherited primary immunodeficiency disorder of phagocytes, characterized by recurrent fungal and bacterial infections. Our aim is to describe the different clinical presentations, non-infectious auto-inflammatory features, types and sites of infections, and to estimate the mortality among our large cohort.

methodsThis is a retrospective study conducted at the Pediatric Department of Cairo University Children's Hospital in Egypt, including cases with a confirmed CGD diagnosis.

resultsOne hundred seventy-three confirmed CGD patients were included. AR-CGD was diagnosed in 132 patients (76.3%) including 83 patients (48%) with p47

conclusionAR-CGD is predominant in Egypt; CGD must always be ruled out in any patient presenting with typical or atypical mycobacterial or BCG-disease.

Indexed as

Granulomatous Disease, ChronicPrimary Immunodeficiency DiseasesChildEgyptHumansNontuberculous MycobacteriaPatientsRetrospective StudiesAR-CGDAutoimmune manifestations in CGDCGD in EgyptInfections in CGDX-linked CGD

Identifiers

PMID37433991
PMCPMC10661789
OpenAlexW4383874996

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.