Evidence map›Paper›PMID 37433966›Full record

ArticleMolecular psychiatry2023

Fetal cannabidiol (CBD) exposure alters thermal pain sensitivity, problem-solving, and prefrontal cortex excitability.

Karli S Swenson, Luis E Gomez Wulschner, Victoria M Hoelscher, Lillian Folts, Kamryn M Korth, Won Chan Oh, Emily Anne Bates

Open access · hybridAbstract read
In one paragraph

Article in Molecular psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Update of the statement on safety of cannabidiol as a novel food.EFSA journal. European Food Safety Authority · 2026
    Article
  3. Article
  4. Article
  5. Cannabidiol alleviates methamphetamine addictionActa pharmaceutica Sinica. B · 2025
    Article
  6. The Current State of Unapproved Cannabidiol Product Use in Children.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. The effects of cannabidiol and its main metabolites on human neural stem cells.Experimental biology and medicine (Maywood, N.J.) · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Karli S SwensonSection of Developmental Biology, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Luis E Gomez WulschnerDepartment of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Victoria M HoelscherDepartment of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Lillian FoltsSection of Developmental Biology, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0002-5832-9410
Kamryn M KorthSection of Developmental Biology, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Won Chan OhDepartment of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Emily Anne BatesSection of Developmental Biology, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Emily.Bates@CUAnschutz.edu.ORCID 0000-0001-6895-8942
University of Colorado Anschutz Medical Campus · US

Funding

NRSA Training CoreTL1TR002533 · NCATS · UNIVERSITY OF COLORADO DENVER · PI CICUTTO, LISA · 2018 to 2022
$3.0M
Serotonergic modulation of excitatory synapse formation and maturation during developmentR01MH124778 · NIMH · UNIVERSITY OF COLORADO DENVER · PI OH, WON CHAN · 2021 to 2025
$1.9M
Ion channel mediated control of mophogen signaling for craniofacial development in mammalsR01DE025311 · NIDCR · UNIVERSITY OF COLORADO DENVER · PI BATES, EMILY · 2018 to 2023
$1.8M
Dissecting neural circuits underlying early life stress-induced PFC dysfunctionR21MH126073 · NIMH · UNIVERSITY OF COLORADO DENVER · PI OH, WON CHAN · 2021 to 2022
$428k
NCATS NIH HHS TL1 TR002533NIDCR NIH HHS R01 DE025311NIMH NIH HHS R01 MH124778NIMH NIH HHS R21 MH126073
6 · The paper itself

Abstract

Thousands of people suffer from nausea with pregnancy each year. Nausea can be alleviated with cannabidiol (CBD), a primary component of cannabis that is widely available. However, it is unknown how fetal CBD exposure affects embryonic development and postnatal outcomes. CBD binds and activates receptors that are expressed in the fetal brain and are important for brain development, including serotonin receptors (5HT

Indexed as

CannabidiolAnimalsFemaleHumansMaleMiceNauseaPainPrefrontal CortexPregnancySunflower OilCannabidiolSunflower Oil

Identifiers

PMID37433966
PMCPMC10618089
OpenAlexW4383913293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.