Evidence map›Paper›PMID 37433797›Full record

ArticleNature communications2023

The role of vaccination and public awareness in forecasts of Mpox incidence in the United Kingdom.

Samuel P C Brand, Massimo Cavallaro, Fergus Cumming, Charlie Turner, Isaac Florence, Paula Blomquist, Joe Hilton, Laura M Guzman-Rincon, Thomas House, D James Nokes and 1 more

Abstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  17. Relationship dynamics and behavioral adaptations in the control of the 2022 mpox epidemic.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  18. Article
  19. Transmission Dynamics of Mpox in Peru During the 2022 Outbreak.The American journal of tropical medicine and hygiene · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Samuel P C BrandThe Zeeman Institute for Systems Biology Infectious Disease Epidemiology Research (SBIDER), Coventry, UK. sam055@mac.com.ORCID 0000-0003-0645-5367
Massimo CavallaroThe Zeeman Institute for Systems Biology Infectious Disease Epidemiology Research (SBIDER), Coventry, UK.ORCID 0000-0002-2365-6024
Fergus CummingUnited Kingdom Health Security Agency, London, UK.
Charlie TurnerUnited Kingdom Health Security Agency, London, UK.
Isaac FlorenceUnited Kingdom Health Security Agency, London, UK.ORCID 0000-0001-8260-1237
Paula BlomquistUnited Kingdom Health Security Agency, London, UK.
Joe HiltonThe Zeeman Institute for Systems Biology Infectious Disease Epidemiology Research (SBIDER), Coventry, UK.
Laura M Guzman-RinconThe Zeeman Institute for Systems Biology Infectious Disease Epidemiology Research (SBIDER), Coventry, UK.ORCID 0000-0003-4592-2896
Thomas HouseDepartment of Mathematics, University of Manchester, Manchester, UK.ORCID 0000-0001-5835-8062
D James NokesThe Zeeman Institute for Systems Biology Infectious Disease Epidemiology Research (SBIDER), Coventry, UK.ORCID 0000-0001-5426-1984
Matt J KeelingThe Zeeman Institute for Systems Biology Infectious Disease Epidemiology Research (SBIDER), Coventry, UK.ORCID 0000-0003-4639-4765

Funding

Department of Health NIHR200411Medical Research Council MR/V038613/1Wellcome TrustWellcome Trust 220985/Z/20/Z
6 · The paper itself

Abstract

Beginning in May 2022, Mpox virus spread rapidly in high-income countries through close human-to-human contact primarily amongst communities of gay, bisexual and men who have sex with men (GBMSM). Behavioural change arising from increased knowledge and health warnings may have reduced the rate of transmission and modified Vaccinia-based vaccination is likely to be an effective longer-term intervention. We investigate the UK epidemic presenting 26-week projections using a stochastic discrete-population transmission model which includes GBMSM status, rate of formation of new sexual partnerships, and clique partitioning of the population. The Mpox cases peaked in mid-July; our analysis is that the decline was due to decreased transmission rate per infected individual and infection-induced immunity among GBMSM, especially those with the highest rate of new partners. Vaccination did not cause Mpox incidence to turn over, however, we predict that a rebound in cases due to behaviour reversion was prevented by high-risk group-targeted vaccination.

Indexed as

Mpox, MonkeypoxSexual and Gender MinoritiesHomosexuality, MaleHumansIncidenceMaleUnited KingdomVaccination

Identifiers

PMID37433797
PMCPMC10336136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.