ArticleBMJ open respiratory research2023
Dysfunctional breathing symptoms, functional impact and quality of life in patients with long COVID-19: a prospective case series.
Article in BMJ open respiratory research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06707623 (Cardiopulmonary Exercise Testing Guided Physiotherapy During Pulmonary Rehabilitation in Patients With Dysfunctional Breathing, a Randomized Controlled Trial), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cardiopulmonary Exercise Testing Guided Physiotherapy During Pulmonary Rehabilitation in Patients With Dysfunctional Breathing, a Randomized Controlled Trial
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Measurement properties of outcome measurement instruments for pediatric dysfunctional breathing: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Pooled it
- Mild hyperventilation with preserved exercise capacity in patients with self-reported long-term dyspnea after COVID-19-a prospective cohort study in a primary healthcare setting.Scandinavian journal of primary health care · 2026Article
- Insular routing to orbitofrontal cortex enables breathing awareness.Science advances · 2026Article
- Echocardiogram Testing in Patients with Post-COVID-19 Condition: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- A comprehensive comparison of primary hyperventilation syndrome versus hyperventilation syndrome secondary to respiratory infections.BMC infectious diseases · 2026Article
- Article
- An objective method to detect sighs during cardio-pulmonary exercise testing.Scientific reports · 2025Article
- Predictability of breathing parameters during cardiopulmonary exercise testing using entropy measurements.Physiological reports · 2025Article
- Insular routing to orbitofrontal cortex enables breathing awareness.medRxiv : the preprint server for health sciences · 2025Article
- Characterization of dysfunctional breathing using cardiopulmonary exercise testing.Physiological reports · 2025Article
- Respiratory burden in post-acute COVID-19 sequelae: a longitudinal study of airway and systemic inflammation and clinical outcomes.ERJ open research · 2025Article
- Characterising dysfunctional breathing seen in post-acute sequelae of SARS-CoV-2 using approximate entropy.ERJ open research · 2025Article
- Comparing methods to measure the dispersion of breathing parameters during exercise testing: A simulation study based on real-life parameters from patients with dysfunctional breathing.Physiological reports · 2025Article
- Article
- Article
- Factors associated with phenotypes of dyspnea in post-COVID-19 condition: a cross-sectional study.Scientific reports · 2024Article
- Dysfunctional Breathing in Children: A Literature Review.Children (Basel, Switzerland) · 2024Review
- Unraveling persistent dyspnea after mild COVID: insights from a case series on hyperventilation provocation tests.Frontiers in physiology · 2024Article
- Decreased physical performance despite objective and subjective maximal exhaustion in post-COVID-19 individuals with fatigue.European journal of medical research · 2023Article
- ERS International Congress 2022: highlights from the Respiratory Clinical Care and Physiology Assembly.ERJ open research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDysfunctional breathing is increasingly recognised after SARS-CoV-2 infection, but the associated symptoms, functional impact and quality of life have not been systematically studied.
methodsThis study describes a prospective case series of 48 patients with dysfunctional breathing based on compatible symptoms and an abnormal breathing pattern during cardiopulmonary exercise testing. Patients with underlying disease that could explain these symptoms were excluded. Median time from COVID-19 to evaluation was 212 (IQR 121) days. Self-administered questionnaires, including the Nijmegen questionnaire, Short-Form (36) Health Survey (SF-36), Hospital Anxiety and Depression Scale, modified Medical Research Council scale, post-COVID-19 Functional Scale, and specific long COVID symptoms, were the outcome measures.
resultsOn average, mean V'O
conclusionsLong COVID patients with dysfunctional breathing have a high burden of symptoms, functional impact and a low quality of life, despite no or negligible organic damage.
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Registered trials
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