Evidence map›Paper›PMID 37432987›Full record

ArticleeLife2023

How enhancers regulate wavelike gene expression patterns.

Christine Mau, Heike Rudolf, Frederic Strobl, Benjamin Schmid, Timo Regensburger, Ralf Palmisano, Ernst H K Stelzer, Leila Taher, Ezzat El-Sherif

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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  4. ATAC-seq in Emerging Model Organisms: Challenges and Strategies.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Christine MauDivision of Developmental Biology, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Heike RudolfDivision of Developmental Biology, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Frederic StroblBuchmann Institute for Molecular Life Sciences (BMLS), Goethe Universität Frankfurt Am Main, Frankfurt am Main, Germany.
Benjamin SchmidOptical Imaging Centre Erlangen (OICE), Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.ORCID 0000-0002-9327-2296
Timo RegensburgerDivision of Developmental Biology, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Ralf PalmisanoOptical Imaging Centre Erlangen (OICE), Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.ORCID 0000-0003-4283-2115
Ernst H K StelzerBuchmann Institute for Molecular Life Sciences (BMLS), Goethe Universität Frankfurt Am Main, Frankfurt am Main, Germany.ORCID 0000-0003-1545-0736
Leila TaherInstitute of Biomedical Informatics, Graz University of Technology, Graz, Austria.ORCID 0000-0002-2013-5426
Ezzat El-SherifDepartment of Biology, University of Texas Rio Grande Valley, Edinburg, United States.ORCID 0000-0003-1738-8139
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEGoethe University Frankfurt · DEGraz University of Technology · ATThe University of Texas Rio Grande Valley · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A key problem in development is to understand how genes turn on or off at the right place and right time during embryogenesis. Such decisions are made by non-coding sequences called 'enhancers.' Much of our models of how enhancers work rely on the assumption that genes are activated de novo as stable domains across embryonic tissues. Such a view has been strengthened by the intensive landmark studies of the early patterning of the anterior-posterior (AP) axis of the

Indexed as

Insect ProteinsTriboliumAnimalsBody PatterningDrosophilaGene ExpressionGene Expression Regulation, DevelopmentalRegulatory Sequences, Nucleic AcidInsect Proteinsclockcomputational biologydevelopmental biologyenhancerspattern formationsystems biologytemporal patterningtriboliumwaves

Identifiers

PMID37432987
PMCPMC10368423
OpenAlexW4383903796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.