SynthesisSpine deformity2023
Vertebral body tethering for idiopathic scoliosis: a systematic review and meta-analysis.
Synthesis in Spine deformity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Posterior spinal fusion versus vertebral body tethering for paediatric scoliosis: a meta-analysis of comparative studies.Spine deformity · 2025Pooled it
- Global evolution of adolescent idiopathic scoliosis research (1990-2025): a bibliometric and visualization analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- The magnitude of postoperative anterior vertebral body tethering scoliosis correction as measured by inter-screw angulation is dependent on the remaining growth potential at the time of surgery.Spine deformity · 2026Article
- Lumbar vertebral body tethering: 2-year multicenter radiographic and reoperation outcomes.Spine deformity · 2026Article
- Growth-Based Decision-Making in Congenital Scoliosis with Multiple Vertebral Anomalies.Journal of clinical medicine · 2026Review
- Vertebral Body Tethering for Adolescent Idiopathic Scoliosis: Quality of Evidence and Recommendations From a Systematic Overview of Systematic Reviews in Literature.International journal of spine surgery · 2025Article
- Segmental range of motion of vertebral body tethering: an in-vitro analysis of single-tether, double-tether, and hybrid constructs.Journal of orthopaedic surgery and research · 2025Article
- Does screw alignment affect tether breakage in vertebral body tethering?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Multicenter validation of a surgical planning tool for lumbar vertebral body tethering simulating growth modulation over 2 years.Spine deformity · 2025Article
- Assessment and Management of Adolescent Idiopathic Scoliosis: From the Perspective of a Physiatrist.Annals of rehabilitation medicine · 2025Article
- Patient education strategies in pediatric orthopaedics: using ChatGPT to answer frequently asked questions on scoliosis.Spine deformity · 2025Article
- Biomechanical restoration in unilateral facet arthroplasty: a cadaveric evaluation.North American Spine Society journal · 2025Article
- Where does the tether break in vertebral body tethering cases? Clinical insights from revision cases after tether breakage.Spine deformity · 2025Article
- Impact of growth on spinal biomechanics and tether force in VBT: a simulation study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- CORR Insights®: How Do Patients Perceive Success and Satisfaction After Vertebral Body Tethering and Fusion for Adolescent Idiopathic Scoliosis? A Qualitative Study.Clinical orthopaedics and related research · 2025Article
- Which Lenke type curve is most appropriate for vertebral body tethering in adolescent idiopathic scoliosis?Spine deformity · 2025Article
- Reducing postoperative morbidity by diminishing chest tube drainage utilizing tranexamic acid following vertebral body tethering for adolescent idiopathic scoliosis.Spine deformity · 2025Article
- Juvenile idiopathic scoliosis treated with anterior vertebral body tethering and disc releases: a case report.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Apical stress redistribution during anterior vertebral body tethering for thoracic adolescent idiopathic scoliosis: a finite element analysis of a novel surgical technique.Spine deformity · 2025Article
- Associations of overweight status with spinal curve correction and complications in patients undergoing vertebral body tethering: a multicenter retrospective review.Spine deformity · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeVertebral body tethering (VBT) is a recent procedure to correct and reduce spinal curves in skeletally immature patients with adolescent idiopathic scoliosis (AIS). The purpose of this systematic review and meta-analysis is to determine the expected curve reduction and potential complications for adolescent patients after VBT.
methodsPubMed, Embase, Google Scholar and Cochrane databases were searched until February 2022. Records were screened against pre-defined inclusion and exclusion criteria. Data sources were prospective and retrospective studies. Demographics, mean differences in Cobb angle, surgical details and complication rates were recorded. Meta-analysis was conducted using a random-effects model.
resultsThis systematic review includes 19 studies, and the meta-analysis includes 16 of these. VBT displayed a statistically significant reduction in Cobb angle from pre-operative to final (minimum 2 years) measurements. The initial mean Cobb angle was 47.8° (CI 95% 42.9-52.7°) and decreased to 22.2° (CI 95% 19.9-24.5°). The mean difference is - 25.8° (CI 95% - 28.9-22.7) (p < 0.01). The overall complication rate was 23% (CI 95% 14.4-31.6%), the most common complication was tether breakage 21.9% (CI 95% 10.6-33.1%). The spinal fusion rate was 7.2% (CI 95% 2.3-12.1%).
conclusionVBT results in a significant reduction of AIS at 2 years of follow-up. Overall complication rate was relatively high although the consequences of the complications are unknown. Further research is required to explore the reasons behind the complication rate and determine the optimal timing for the procedure. VBT remains a promising new procedure that is effective at reducing scoliotic curves and preventing spinal fusion in the majority of patients. LEVEL OF EVIDENCE: Systematic review of Therapeutic Studies with evidence level II-IV.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.