Evidence map›Paper›PMID 37432526›Full record

ArticleIrish journal of medical science2024

Risk factors for rebleeding in gastroduodenal ulcers.

Nobuhito Ito, Kohei Funasaka, Toshihisa Fujiyoshi, Kazuki Nishida, Yusuke Satta, Kazuhiro Furukawa, Naomi Kakushima, Satoshi Furune, Eri Ishikawa, Yasuyuki Mizutani and 11 more

Abstract read
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In one paragraph

Article in Irish journal of medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Trends in upper gastrointestinal bleeding management.World journal of clinical cases · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 1 country.

Nobuhito ItoDepartment of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Aichi, Japan.
Kohei FunasakaDepartment of Gastroenterology and Hepatology, Fujita Health University School of Medicine, 1-98 Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan. k-funa@med.nagoya-u.ac.jp.ORCID http://orcid.org/0000-0002-3869-1420
Toshihisa FujiyoshiJapanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital, Aichi, Japan.
Kazuki NishidaDepartment of Biostatistics Section, Center for Advanced Medicine and Clinical Research, Nagoya University Graduate School of Medicine, Aichi, Japan.
Yusuke SattaKonan Kosei Hospital, Aichi, Japan.
Kazuhiro FurukawaDepartment of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Aichi, Japan.
Naomi KakushimaDepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Satoshi FuruneDepartment of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Aichi, Japan.
Eri IshikawaDepartment of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Aichi, Japan.
Yasuyuki MizutaniDepartment of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Aichi, Japan.
Tsunaki SawadaDepartment of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Aichi, Japan.
Keiko MaedaDepartment of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Aichi, Japan.
Takuya IshikawaDepartment of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Aichi, Japan.
Takeshi YamamuraDepartment of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Aichi, Japan.
Eizaburo OhnoDepartment of Gastroenterology and Hepatology, Fujita Health University School of Medicine, 1-98 Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan.
Masanao NakamuraDepartment of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Aichi, Japan.
Ryoji MiyaharaDepartment of Gastroenterology and Hepatology, Fujita Health University School of Medicine, 1-98 Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan.
Yoji SasakiKonan Kosei Hospital, Aichi, Japan.
Jun-Ichi HarutaDepartment of Biostatistics Section, Center for Advanced Medicine and Clinical Research, Nagoya University Graduate School of Medicine, Aichi, Japan.
Mitsuhiro FujishiroDepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Hiroki KawashimaDepartment of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Aichi, Japan.
Nagoya University · JPFujita Health University · JPKonan Kosei Hospital · JPThe University of Tokyo · JPJapanese Red Cross Nagoya Daiichi Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRebleeding after hemostasis of the gastroduodenal ulcer (GDU) is one of the indicators associated with death among GDU patients. However, there are few studies on risk score that contribute to rebleeding after endoscopic hemostasis of bleeding peptic ulcers.

aimsThe aim of this study was to identify factors associated with rebleeding, including patient factors, after endoscopic hemostasis of bleeding gastroduodenal ulcers and to stratify the risk of rebleeding.

methodsWe retrospectively enrolled 587 consecutive patients who were treated for Forrest Ia to IIa bleeding gastroduodenal ulcers with endoscopic hemostasis at three institutions. Risk factors associated with rebleeding were assessed using univariate and multivariate logistic regression analyses. The Rebleeding Nagoya University (Rebleeding-N) scoring system was developed based on the extracted factors. The Rebleeding-N score was internally validated using bootstrap resampling methods.

resultsSixty-four patients (11%) had rebleeding after hemostasis of gastroduodenal ulcers. Multivariate logistic regression analysis revealed four independent rebleeding risk factors: blood transfusion, albumin <2.5, duodenal ulcer, and diameter of the exposed vessel ≧2 mm. Patients with 4 risk factors in the Rebleeding-N score had a 54% rebleeding rate, and patients with 3 risk factors had 44% and 25% rebleeding rates. In the internal validation, the mean area under the curve of the Rebleeding-N score was 0.830 (95% CI = 0.786-0.870).

conclusionsRebleeding after clip hemostasis of bleeding gastroduodenal ulcers was associated with blood transfusion, albumin <2.5, diameter of the exposed vessel ≧2 mm, and duodenal ulcer. The Rebleeding-N score was able to stratify the risk of rebleeding.

Indexed as

Duodenal UlcerPeptic UlcerAlbuminsHumansPeptic Ulcer HemorrhageRecurrenceRetrospective StudiesRisk FactorsAlbuminsEndoscopic interventionGastrointestinal bleedingRebleedingRetrospective study

Identifiers

PMID37432526
OpenAlexW4383872156

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.