ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2023
Externalization of an infected vagus nerve stimulator generator without a break in anti-seizure therapy: a technical note.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionVagus nerve stimulation (VNS) is a widely used treatment for drug-resistant epilepsy. An infection of the VNS generator pocket occurs in 3-8% of cases. Current standard of care requires the removal of the device, antibiotic therapy, and then replacement of the device. The consequential break in VNS therapy leaves patients highly susceptible to seizures.
methodsRetrospective case report.
resultsThe externalized generator continued to provide electroceutical coverage of the patient's seizures while the pocket was sterilized with IV antibiotics as well as betadine and local antibiotics. The externalized generator was kept safe against the patient's chest with ioban and an entriely new system was implanted on post-externalization day 5. The patient is now 7 months post-operative and without any evidence of infection.
conclusionsWe report successful management of an infected VNS generator with externalization and short interval replacement of the entire system without any break in anti-seizure therapy.
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