Evidence map›Paper›PMID 37432370›Full record

ArticleNutrients2023

Influence of the TAS2R38 Gene Single Nucleotide Polymorphisms in Metabolism and Anthropometry in Thyroid Dysfunction.

Marta Mendes Costa, Alda Pereira Da Silva, Carolina Santos, Joana Ferreira, Mário Rui Mascarenhas, Manuel Bicho, Ana Paula Barbosa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
  3. Extragustatory bitter taste receptors in head and neck health and disease.Journal of molecular medicine (Berlin, Germany) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Marta Mendes CostaEcogenetics and Human Health Unity, Institute for Environmental Health (ISAMB), Genetics Laboratory, Associate Laboratory TERRA, Faculty of Medicine, Lisbon University, 1649-028 Lisbon, Portugal.ORCID 0009-0005-7722-0268
Alda Pereira Da SilvaEcogenetics and Human Health Unity, Institute for Environmental Health (ISAMB), Genetics Laboratory, Associate Laboratory TERRA, Faculty of Medicine, Lisbon University, 1649-028 Lisbon, Portugal.
Carolina SantosEcogenetics and Human Health Unity, Institute for Environmental Health (ISAMB), Genetics Laboratory, Associate Laboratory TERRA, Faculty of Medicine, Lisbon University, 1649-028 Lisbon, Portugal.
Joana FerreiraEcogenetics and Human Health Unity, Institute for Environmental Health (ISAMB), Genetics Laboratory, Associate Laboratory TERRA, Faculty of Medicine, Lisbon University, 1649-028 Lisbon, Portugal.ORCID 0000-0002-3527-3274
Mário Rui MascarenhasEcogenetics and Human Health Unity, Institute for Environmental Health (ISAMB), Genetics Laboratory, Associate Laboratory TERRA, Faculty of Medicine, Lisbon University, 1649-028 Lisbon, Portugal.
Manuel BichoEcogenetics and Human Health Unity, Institute for Environmental Health (ISAMB), Genetics Laboratory, Associate Laboratory TERRA, Faculty of Medicine, Lisbon University, 1649-028 Lisbon, Portugal.ORCID 0000-0002-5773-5687
Ana Paula BarbosaEcogenetics and Human Health Unity, Institute for Environmental Health (ISAMB), Genetics Laboratory, Associate Laboratory TERRA, Faculty of Medicine, Lisbon University, 1649-028 Lisbon, Portugal.
University of Lisbon · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gene TAS2R38 single nucleotide polymorphisms (SNPs-P49A, A262V and V296I) can condition bitter tasting by PAV (proline-alanine-valine) and non-bitter-tasting by AVI (alanine-valine-isoleucine) homozygosity. We evaluated this polymorphisms association with thyroid function, metabolism and anthropometry parameters determined by: Endpoint analysis (SNPs); DXA (fat mass-%, total fat mass-kg, lean mass-kg); Standard methods (lipid metabolism parameters, HbA1c-%, glycemia-mg/dL, insulinemia-µIU/mL, HOMA-IR, uricemia-mg/dL, calcemia-mg/dL and BMI-kg/m

Indexed as

HyperthyroidismHypothyroidismAlanineAnthropometryGlycated HemoglobinHumansIsoleucineLeptinPolymorphism, Single NucleotideProlineAlanineGlycated HemoglobinIsoleucineLeptinProlinebitter tastehyperthyroidismhypothyroidismpolymorphisms P49A/A262V/V296ITAS2R38

Identifiers

PMID37432370
PMCPMC10180943
OpenAlexW4382341080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.