Evidence map›Paper›PMID 37432363›Full record

ArticleNutrients2023

Post-Prandial Cognitive and Blood Pressure Effects of a DHA-Rich Omega-3 Powder in Middle-Aged Males: A Pilot Study.

Andrew Pipingas, Jeffery Michael Reddan, Sarah Gauci, Lauren M Young, Greg Kennedy, Renee Rowsell, Rebecca King, Sam Spiteri, Anne Marie Minihane, Andrew Scholey

Abstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrew PipingasCentre for Mental Health and Brain Sciences, Swinburne University of Technology, Hawthorn, VIC 3122, Australia.
Jeffery Michael ReddanCentre for Mental Health and Brain Sciences, Swinburne University of Technology, Hawthorn, VIC 3122, Australia.
Sarah GauciFood & Mood Centre, The Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine, Deakin University, Geelong, VIC 3220, Australia.ORCID 0000-0002-1907-1066
Lauren M YoungCentre for Mental Health and Brain Sciences, Swinburne University of Technology, Hawthorn, VIC 3122, Australia.ORCID 0000-0002-2020-0400
Greg KennedyCentre for Mental Health and Brain Sciences, Swinburne University of Technology, Hawthorn, VIC 3122, Australia.
Renee RowsellCentre for Mental Health and Brain Sciences, Swinburne University of Technology, Hawthorn, VIC 3122, Australia.
Rebecca KingCentre for Mental Health and Brain Sciences, Swinburne University of Technology, Hawthorn, VIC 3122, Australia.
Sam SpiteriCentre for Mental Health and Brain Sciences, Swinburne University of Technology, Hawthorn, VIC 3122, Australia.
Anne Marie MinihaneNorwich Medical School, University of East Anglia, Norwich, NR4 7TJ, UK.
Andrew ScholeyCentre for Mental Health and Brain Sciences, Swinburne University of Technology, Hawthorn, VIC 3122, Australia.ORCID 0000-0003-4484-5462

Funding

Nu-Mega Ingredients (Altona North, Victoria, Australia) NM001
6 · The paper itself

Abstract

The use of omega-3 polyunsaturated fatty acid (ω-3 PUFA) supplements is increasingly common among middle-aged and older adults. Users of ω-3 PUFA supplements often report using such supplements to support cognitive health, despite mixed findings reported within the ω-3 PUFA literature. To date, very few studies have explored cognitive effects in distinctly middle-aged (40 to 60 years) adults, and none have examined the acute effects (in the hours following a single dose) on cognitive performance. The current study evaluated whether a single dose of ω-3 PUFA (4020 mg docosahexaenoic acid and 720 mg eicosapentaenoic acid) influences cognitive performance and cardiovascular function in middle-aged males. Cognitive performance and cardiovascular function were assessed before and 3.5-4 h after consumption of a high dose of ω-3 PUFA (DHA + EPA) or placebo, incorporated into a standardized meal (i.e., single serve of Greek yogurt). In this study of middle-aged males, no significant differential treatment effects were observed for cognitive performance. However, a significant reduction in aortic systolic blood pressure (pre-dose to post-dose) was apparent following consumption of the ω-3 PUFA (DHA + EPA) treatment (mean difference = -4.11 mmHg,

Indexed as

Docosahexaenoic AcidsFatty Acids, Omega-3AdultBlood PressureCognitionHumansMaleMiddle AgedPilot ProjectsPowdersDocosahexaenoic AcidsFatty Acids, Omega-3Powdersacuteblood pressurecognitionDHAmiddle-agednootropicomega-3 PUFA

Identifiers

PMID37432363
PMCPMC10181233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.