Evidence map›Paper›PMID 37432217›Full record

ArticleNutrients2023

The Benefits of Olive Oil for Skin Health: Study on the Effect of Hydroxytyrosol, Tyrosol, and Oleocanthal on Human Fibroblasts.

Anabel González-Acedo, Javier Ramos-Torrecillas, Rebeca Illescas-Montes, Víctor J Costela-Ruiz, Concepción Ruiz, Lucía Melguizo-Rodríguez, Olga García-Martínez

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Histological Evaluation ofBiomedicines · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. In vitro antibiofilm activity of tyrosol against single and dual-species biofilms ofTurkish journal of biology = Turk biyoloji dergisi · 2025
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Anabel González-AcedoBiomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada, C/Santander, 1, 52005 Melilla, Spain.ORCID 0000-0002-8132-305X
Javier Ramos-TorrecillasBiomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada, Avda. Ilustración 60, 18016 Granada, Spain.ORCID 0000-0002-6631-7866
Rebeca Illescas-MontesBiomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada, Avda. Ilustración 60, 18016 Granada, Spain.ORCID 0000-0001-9795-8159
Víctor J Costela-RuizInstitute of Biosanitary Research, ibs.Granada, C/Doctor Azpitarte 4, 4a Planta, 18012 Granada, Spain.ORCID 0000-0001-7285-6615
Concepción RuizBiomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada, Avda. Ilustración 60, 18016 Granada, Spain.ORCID 0000-0003-4332-6812
Lucía Melguizo-RodríguezBiomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada, Avda. Ilustración 60, 18016 Granada, Spain.ORCID 0000-0002-9176-6997
Olga García-MartínezBiomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada, Avda. Ilustración 60, 18016 Granada, Spain.ORCID 0000-0003-1912-4639
Universidad de Granada · ES

Funding

FEDER/Junta de Andalucía-Consejería de Universidad, Investigación e Innovación B-CTS-134-UGR20
6 · The paper itself

Abstract

Fibroblasts contribute to maintaining tissue integrity and homeostasis and are a key cell population in wound healing. This cell population can be stimulated by some bioactive compounds such as extra virgin olive oil (EVOO) polyphenols. The aim of this study was to determine the effects of hydroxytyrosol (htyr), tyrosol (tyr), and oleocanthal (ole) phenolic compounds present in EVOO on the proliferation, migration, cell cycle, and antigenic profile of cultured human fibroblasts. CCD-1064Sk human fibroblast cells were treated for 24 h with each polyphenol at doses ranging 10

Indexed as

FibroblastsPolyphenolsAldehydesCyclopentane MonoterpenesHumansOlive OilPhenolsPhenylethyl Alcohol3,4-dihydroxyphenylethanol4-hydroxyphenylethanolAldehydesCyclopentane MonoterpenesoleocanthalOlive OilPhenolsPhenylethyl AlcoholPolyphenolsextra virgin olive oilfibroblastsphenolic compoundstissue regenerationwound healing

Identifiers

PMID37432217
PMCPMC10181161
OpenAlexW4367054434

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.