Evidence map›Paper›PMID 37432191›Full record

Trial reportNutrients2023

The Effects of Multiple Micronutrient Fortified Beverage and Responsive Caregiving Interventions on Early Childhood Development, Hemoglobin, and Ferritin among Infants in Rural Guatemala.

Alysse J Kowalski, Victor Alfonso Mayen, Silvia de Ponce, Kaley B Lambden, Nick Tilton, Lisa M Villanueva, Ana M Palacios, Gregory A Reinhart, Kristen M Hurley, Maureen M Black

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Approaches to Address the Anemia Challenge.The Journal of nutrition · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alysse J KowalskiDepartment of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA.ORCID 0000-0001-7200-9694
Victor Alfonso MayenAsociación para la Prevención y Estudio del VIH/Sida, Retalhuleu 11001, Guatemala.ORCID 0000-0003-4694-7569
Silvia de PonceAsociación para la Prevención y Estudio del VIH/Sida, Retalhuleu 11001, Guatemala.
Kaley B LambdenDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Nick TiltonDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD 21202, USA.
Lisa M VillanuevaThe Mathile Institute for the Advancement of Human Nutrition, Dayton, OH 45414, USA.
Ana M PalaciosThe Mathile Institute for the Advancement of Human Nutrition, Dayton, OH 45414, USA.ORCID 0000-0002-9489-2219
Gregory A ReinhartThe Mathile Institute for the Advancement of Human Nutrition, Dayton, OH 45414, USA.
Kristen M HurleyDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Maureen M BlackDepartment of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA.ORCID 0000-0002-6427-4639

Funding

NRSA Training CoreTL1TR003100 · NCATS · JOHNS HOPKINS UNIVERSITY · PI SAHA, SOMNATH · 2019 to 2023
$4.5M
NCATS NIH HHS TL1 TR003100
6 · The paper itself

Abstract

Undernutrition and a lack of learning opportunities can jeopardize long-term growth and development among infants in low- and middle-income countries. We conducted a 6-month 2 × 2 cluster-randomized trial to assess the effects of multiple micronutrient-fortified beverages and responsive caregiving interventions among infants 6-18 months in 72 community sectors in southwest Guatemala. We administered baseline and endline assessments of childhood development (Bayley Scales of Infant and Toddler Development) and socioemotional development (Brief Infant Toddler Socio-Emotional Assessment) and measured ferritin and hemoglobin on a subsample. The trial was analyzed using linear mixed models. At the baseline, the mean age (SD) was 13.0 (4.6) months, including 49% males, 32% who were stunted, 55% who were anemic, and 58% who were iron deficient. At the endline (

Indexed as

Child DevelopmentFerritinsBeveragesFemaleGuatemalaHemoglobinsHumansInfantMaleMicronutrientsFerritinsHemoglobinsMicronutrientsearly child developmentferritinGuatemalahemoglobininfantmultiple micronutrient supplementationresponsive caregivingsocioemotional development

Identifiers

PMID37432191
PMCPMC10181059

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.