Evidence map›Paper›PMID 37432032›Full record

ArticlemBio2023

Peter J Brechting, Chandan Shah, Liva Rakotondraibe, Qian Shen, Chad A Rappleye

Open access · goldAbstract read
In one paragraph

Article in mBio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Tools for genetic manipulation of the endemic fungal pathogen,bioRxiv : the preprint server for biology · 2025
    Article
  6. Telomeric assemblies ofbioRxiv : the preprint server for biology · 2025
    Article
  7. Review
  8. Genotypic diversity, virulence, and molecular genetic tools inMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Peter J BrechtingDepartment of Microbiology, Ohio State University , Columbus, Ohio, USA.ORCID 0009-0001-7632-3725
Chandan ShahDepartment of Microbiology, Ohio State University , Columbus, Ohio, USA.
Liva RakotondraibeDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Ohio State University , Columbus, Ohio, USA.
Qian ShenDepartment of Biology, Rhodes College , Memphis, Tennessee, USA.ORCID 0000-0002-9001-7636
Chad A RappleyeDepartment of Microbiology, Ohio State University , Columbus, Ohio, USA.ORCID 0000-0001-7880-5958
The Ohio State University · USRhodes College · US

Funding

Intracellular Proliferation of the fungal pathogen Histoplasma capsulatumR01AI148561 · NIAID · OHIO STATE UNIVERSITY · PI Chad A Rappleye · 2020 to 2026
$2.5M
Forward genetics-based discovery of Histoplasma virulence genesR03AI111015 · NIAID · OHIO STATE UNIVERSITY · PI RAPPLEYE, CHAD A · 2014 to 2015
$147k
NIAID NIH HHS R01 AI148561NIAID NIH HHS R03 AI111015
6 · The paper itself

Abstract

Peroxisomes are versatile eukaryotic organelles essential for many functions in fungi, including fatty acid metabolism, reactive oxygen species detoxification, and secondary metabolite biosynthesis. A suite of Pex proteins (peroxins) maintains peroxisomes, while peroxisomal matrix enzymes execute peroxisome functions. Insertional mutagenesis identified peroxin genes as essential components supporting the intraphagosomal growth of the fungal pathogen

Indexed as

HistoplasmaAdaptation, PhysiologicalPeroxinsPeroxisomesSiderophoresVirulencePeroxinsSiderophoresHistoplasmairon acquisitionmacrophagesperoxisomesiderophoresvirulence

Identifiers

PMID37432032
PMCPMC10470777
OpenAlexW4383872194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.