Evidence map›Paper›PMID 37432011›Full record

ArticlemSystems2023

Paired associated SARS-CoV-2 spike variable positions: a network analysis approach to emerging variants.

Yiannis Manoussopoulos, Cleo Anastassopoulou, John P A Ioannidis, Athanasios Tsakris

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSystems, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 74% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Yiannis ManoussopoulosDepartment of Microbiology, Medical School, National and Kapodistrian University of Athens , Athens, Greece.ORCID 0000-0002-6065-7368
Cleo AnastassopoulouDepartment of Microbiology, Medical School, National and Kapodistrian University of Athens , Athens, Greece.ORCID 0000-0001-7666-9198
John P A IoannidisDepartment of Medicine, Stanford University , Stanford, California, USA.ORCID 0000-0003-3118-6859
Athanasios TsakrisDepartment of Microbiology, Medical School, National and Kapodistrian University of Athens , Athens, Greece.ORCID 0000-0003-0656-4715
National and Kapodistrian University of Athens · GRStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amino acids in variable positions of proteins may be correlated, with potential structural and functional implications. Here, we apply exact tests of independence in R × C contingency tables to examine noise-free associations between variable positions of the SARS-CoV-2 spike protein, using as a paradigm sequences from Greece deposited in GISAID (

Indexed as

Antifibrinolytic AgentsCOVID-19Amino AcidsHumansSARS-CoV-2Spike Glycoprotein, CoronavirusAmino AcidsAntifibrinolytic AgentsSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2COVID-19evolutionnetwork analysisSARS-CoV-2 variantsspike

Identifiers

PMID37432011
PMCPMC10469592
OpenAlexW4383872606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.