Evidence map›Paper›PMID 37431920›Full record

ArticleThe EMBO journal2023

Plant YTHDF proteins are direct effectors of antiviral immunity against an N6-methyladenosine-containing RNA virus.

Mireya Martínez-Pérez, Frederic Aparicio, Laura Arribas-Hernández, Mathias Due Tankmar, Sarah Rennie, Sören von Bülow, Kresten Lindorff-Larsen, Peter Brodersen, Vicente Pallas

Abstract read
In one paragraph

Article in The EMBO journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. CDS-localized mNature plants · 2026
    Article
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  4. The expanding role of mAdvanced biotechnology · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. ALKBH1L Is an mPlants (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Molecular drivers of RNA phase separation.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Role of mEpigenomes · 2025
    Review
  12. The role of NTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Review
  13. WTAP/YTHDF1-mediated mJournal of advanced research · 2025
    Article
  14. Prediction of phase-separation propensities of disordered proteins from sequence.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Review
  16. Review
  17. Reading mJournal of integrative plant biology · 2024
    Review
  18. Article
  19. Article
  20. Recent insights into NCurrent opinion in genetics & development · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Mireya Martínez-PérezInstituto de Biología Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas, Universitat Politècnica de València, Valencia, Spain.ORCID 0000-0003-1864-8473
Frederic AparicioInstituto de Biología Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas, Universitat Politècnica de València, Valencia, Spain.ORCID 0000-0002-1586-9978
Laura Arribas-HernándezDepartment of Biology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-0605-0407
Mathias Due TankmarDepartment of Biology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-6311-9381
Sarah RennieDepartment of Biology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-9731-6957
Sören von BülowDepartment of Biology, University of Copenhagen, Copenhagen, Denmark.
Kresten Lindorff-LarsenDepartment of Biology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-4750-6039
Peter BrodersenDepartment of Biology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-1083-1150
Vicente PallasInstituto de Biología Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas, Universitat Politècnica de València, Valencia, Spain.ORCID 0000-0003-4954-989X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In virus-host interactions, nucleic acid-directed first lines of defense that allow viral clearance without compromising growth are of paramount importance. Plants use the RNA interference pathway as a basal antiviral immune system, but additional RNA-based mechanisms of defense also exist. The infectivity of a plant positive-strand RNA virus, alfalfa mosaic virus (AMV), relies on the demethylation of viral RNA by the recruitment of the cellular N6-methyladenosine (m

Indexed as

ArabidopsisArabidopsis ProteinsRNA VirusesIntracellular Signaling Peptides and ProteinsPlant ProteinsRNA-Binding ProteinsRNA, ViralArabidopsis ProteinsECT2 protein, ArabidopsisIntracellular Signaling Peptides and ProteinsPlant ProteinsRNA-Binding ProteinsRNA, ViralECTsIDRsN6-methyladenosine (m6A)plant-virus interactionRNA methylation

Identifiers

PMID37431920
PMCPMC10505913

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.